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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CWC22
All Species:
21.21
Human Site:
S727
Identified Species:
35.9
UniProt:
Q9HCG8
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCG8
NP_065994.1
908
105535
S727
K
G
H
G
K
T
R
S
K
E
V
D
K
L
I
Chimpanzee
Pan troglodytes
XP_001157639
909
105673
S728
K
G
H
G
K
T
R
S
K
E
V
D
K
L
I
Rhesus Macaque
Macaca mulatta
XP_001100012
907
105697
S727
K
G
H
G
K
T
R
S
K
E
V
D
K
L
I
Dog
Lupus familis
XP_545549
908
105482
S727
K
G
Q
G
N
S
R
S
K
E
V
D
K
L
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8C5N3
908
104755
G732
K
R
Q
G
K
A
R
G
E
E
V
D
K
L
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515527
921
106628
S741
K
V
E
R
K
K
K
S
K
E
A
D
K
V
T
Chicken
Gallus gallus
Q5ZKA3
926
108657
R730
R
E
S
D
K
A
S
R
K
K
Q
E
K
K
R
Frog
Xenopus laevis
Q52KN9
803
92701
M641
F
Q
E
L
C
E
Y
M
G
L
P
K
L
N
A
Zebra Danio
Brachydanio rerio
Q08C72
985
113331
S820
S
G
K
K
K
D
K
S
K
S
K
K
S
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VJ87
1330
151618
K992
R
K
D
K
D
K
K
K
S
K
K
A
T
K
E
Honey Bee
Apis mellifera
XP_001120152
706
80124
T544
P
R
D
D
P
K
N
T
R
F
A
I
N
F
F
Nematode Worm
Caenorhab. elegans
Q17336
897
104250
S731
D
S
S
S
S
S
E
S
E
P
E
P
P
K
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53333
577
67276
Q415
T
E
E
E
S
C
P
Q
G
R
I
F
I
K
F
Red Bread Mold
Neurospora crassa
Q7RX84
1010
113982
S781
R
S
Y
S
R
S
V
S
K
S
V
S
R
S
P
Conservation
Percent
Protein Identity:
100
99.2
97.2
93.2
N.A.
84.2
N.A.
N.A.
77.5
70.6
67.1
60.9
N.A.
39.8
45.5
45.9
N.A.
Protein Similarity:
100
99.4
98.4
95.6
N.A.
90
N.A.
N.A.
86.5
80.2
74.6
71.8
N.A.
52.1
58.9
65.7
N.A.
P-Site Identity:
100
100
100
80
N.A.
60
N.A.
N.A.
46.6
20
0
26.6
N.A.
0
0
6.6
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
66.6
N.A.
N.A.
60
40
0
33.3
N.A.
20
13.3
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.2
38.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.9
55.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
15
0
0
0
0
15
8
0
0
15
% A
% Cys:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
15
15
8
8
0
0
0
0
0
43
0
0
0
% D
% Glu:
0
15
22
8
0
8
8
0
15
43
8
8
0
0
8
% E
% Phe:
8
0
0
0
0
0
0
0
0
8
0
8
0
8
15
% F
% Gly:
0
36
0
36
0
0
0
8
15
0
0
0
0
0
0
% G
% His:
0
0
22
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
8
8
8
0
29
% I
% Lys:
43
8
8
15
50
22
22
8
58
15
15
15
50
29
15
% K
% Leu:
0
0
0
8
0
0
0
0
0
8
0
0
8
36
0
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
8
0
0
0
0
0
8
8
0
% N
% Pro:
8
0
0
0
8
0
8
0
0
8
8
8
8
0
8
% P
% Gln:
0
8
15
0
0
0
0
8
0
0
8
0
0
0
0
% Q
% Arg:
22
15
0
8
8
0
36
8
8
8
0
0
8
0
8
% R
% Ser:
8
15
15
15
15
22
8
58
8
15
0
8
8
15
0
% S
% Thr:
8
0
0
0
0
22
0
8
0
0
0
0
8
0
8
% T
% Val:
0
8
0
0
0
0
8
0
0
0
43
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _