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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CWC22
All Species:
28.48
Human Site:
S889
Identified Species:
48.21
UniProt:
Q9HCG8
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCG8
NP_065994.1
908
105535
S889
S
S
R
Y
S
E
Q
S
R
E
S
K
K
N
Q
Chimpanzee
Pan troglodytes
XP_001157639
909
105673
S890
S
S
R
Y
S
E
Q
S
R
E
S
K
K
N
Q
Rhesus Macaque
Macaca mulatta
XP_001100012
907
105697
S888
S
S
R
Y
S
E
Q
S
R
E
S
K
K
N
Q
Dog
Lupus familis
XP_545549
908
105482
S888
S
S
R
Y
S
T
Q
S
R
E
S
K
K
H
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8C5N3
908
104755
S889
P
G
R
R
P
E
Q
S
R
E
S
K
R
S
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515527
921
106628
S902
P
N
R
H
S
E
Q
S
R
E
S
R
K
H
Q
Chicken
Gallus gallus
Q5ZKA3
926
108657
Y907
Y
N
H
Y
S
D
Q
Y
R
E
S
R
K
H
E
Frog
Xenopus laevis
Q52KN9
803
92701
Q785
E
A
P
K
H
K
H
Q
K
E
K
Y
D
D
K
Zebra Danio
Brachydanio rerio
Q08C72
985
113331
N967
L
E
R
A
D
K
E
N
R
H
S
D
R
Y
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VJ87
1330
151618
S1286
S
D
R
E
K
E
R
S
R
A
K
E
R
E
R
Honey Bee
Apis mellifera
XP_001120152
706
80124
A688
A
V
T
V
T
A
A
A
A
T
V
V
V
E
I
Nematode Worm
Caenorhab. elegans
Q17336
897
104250
D876
D
D
R
K
T
R
R
D
R
S
E
E
R
G
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53333
577
67276
S559
S
R
T
P
P
R
G
S
R
N
H
R
N
R
S
Red Bread Mold
Neurospora crassa
Q7RX84
1010
113982
N975
S
P
S
P
V
V
G
N
N
K
R
R
R
S
Y
Conservation
Percent
Protein Identity:
100
99.2
97.2
93.2
N.A.
84.2
N.A.
N.A.
77.5
70.6
67.1
60.9
N.A.
39.8
45.5
45.9
N.A.
Protein Similarity:
100
99.4
98.4
95.6
N.A.
90
N.A.
N.A.
86.5
80.2
74.6
71.8
N.A.
52.1
58.9
65.7
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
60
N.A.
N.A.
66.6
46.6
6.6
20
N.A.
33.3
0
13.3
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
73.3
N.A.
N.A.
93.3
80
40
53.3
N.A.
60
20
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.2
38.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.9
55.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
8
0
8
8
8
8
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
15
0
0
8
8
0
8
0
0
0
8
8
8
0
% D
% Glu:
8
8
0
8
0
43
8
0
0
58
8
15
0
15
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
15
0
0
0
0
0
0
8
8
% G
% His:
0
0
8
8
8
0
8
0
0
8
8
0
0
22
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
0
0
15
8
15
0
0
8
8
15
36
43
0
15
% K
% Leu:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
15
0
0
0
0
0
15
8
8
0
0
8
22
0
% N
% Pro:
15
8
8
15
15
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
50
8
0
0
0
0
0
0
43
% Q
% Arg:
0
8
65
8
0
15
15
0
79
0
8
29
36
8
8
% R
% Ser:
50
29
8
0
43
0
0
58
0
8
58
0
0
15
8
% S
% Thr:
0
0
15
0
15
8
0
0
0
8
0
0
0
0
0
% T
% Val:
0
8
0
8
8
8
0
0
0
0
8
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
36
0
0
0
8
0
0
0
8
0
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _