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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CWC22
All Species:
18.79
Human Site:
T650
Identified Species:
31.79
UniProt:
Q9HCG8
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCG8
NP_065994.1
908
105535
T650
L
R
E
H
L
K
N
T
P
K
V
I
V
A
Q
Chimpanzee
Pan troglodytes
XP_001157639
909
105673
T651
L
R
E
H
L
K
N
T
P
K
V
I
V
A
Q
Rhesus Macaque
Macaca mulatta
XP_001100012
907
105697
T650
L
R
E
H
L
K
N
T
P
K
V
I
V
A
Q
Dog
Lupus familis
XP_545549
908
105482
T650
L
R
E
H
L
K
N
T
P
K
V
I
V
A
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8C5N3
908
104755
T649
L
R
E
H
L
K
N
T
P
K
V
I
V
A
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515527
921
106628
A660
L
R
E
H
L
K
N
A
P
K
M
I
M
T
Q
Chicken
Gallus gallus
Q5ZKA3
926
108657
A653
L
R
E
H
L
K
N
A
P
K
M
I
M
T
Q
Frog
Xenopus laevis
Q52KN9
803
92701
K565
A
G
R
F
C
L
L
K
K
E
Y
L
E
A
F
Zebra Danio
Brachydanio rerio
Q08C72
985
113331
A744
L
R
E
H
L
K
N
A
P
K
M
I
M
T
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VJ87
1330
151618
A906
L
R
R
F
L
K
N
A
P
K
S
V
P
A
I
Honey Bee
Apis mellifera
XP_001120152
706
80124
S468
T
N
K
L
R
N
V
S
K
F
F
A
H
L
L
Nematode Worm
Caenorhab. elegans
Q17336
897
104250
A655
P
R
T
N
P
N
S
A
R
F
S
I
N
F
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53333
577
67276
F339
S
S
L
Q
E
S
T
F
S
K
F
Y
S
I
L
Red Bread Mold
Neurospora crassa
Q7RX84
1010
113982
M703
M
R
T
F
L
A
N
M
P
K
P
A
L
P
A
Conservation
Percent
Protein Identity:
100
99.2
97.2
93.2
N.A.
84.2
N.A.
N.A.
77.5
70.6
67.1
60.9
N.A.
39.8
45.5
45.9
N.A.
Protein Similarity:
100
99.4
98.4
95.6
N.A.
90
N.A.
N.A.
86.5
80.2
74.6
71.8
N.A.
52.1
58.9
65.7
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
73.3
73.3
6.6
73.3
N.A.
53.3
0
13.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
86.6
86.6
20
86.6
N.A.
60
13.3
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.2
38.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.9
55.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
33.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
8
0
36
0
0
0
15
0
50
8
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
58
0
8
0
0
0
0
8
0
0
8
0
0
% E
% Phe:
0
0
0
22
0
0
0
8
0
15
15
0
0
8
15
% F
% Gly:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
58
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
65
0
8
8
% I
% Lys:
0
0
8
0
0
65
0
8
15
79
0
0
0
0
0
% K
% Leu:
65
0
8
8
72
8
8
0
0
0
0
8
8
8
15
% L
% Met:
8
0
0
0
0
0
0
8
0
0
22
0
22
0
0
% M
% Asn:
0
8
0
8
0
15
72
0
0
0
0
0
8
0
0
% N
% Pro:
8
0
0
0
8
0
0
0
72
0
8
0
8
8
0
% P
% Gln:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
58
% Q
% Arg:
0
79
15
0
8
0
0
0
8
0
0
0
0
0
0
% R
% Ser:
8
8
0
0
0
8
8
8
8
0
15
0
8
0
0
% S
% Thr:
8
0
15
0
0
0
8
36
0
0
0
0
0
22
0
% T
% Val:
0
0
0
0
0
0
8
0
0
0
36
8
36
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _