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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CWC22
All Species:
31.52
Human Site:
Y245
Identified Species:
53.33
UniProt:
Q9HCG8
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCG8
NP_065994.1
908
105535
Y245
I
L
N
F
R
K
G
Y
R
R
N
D
K
Q
L
Chimpanzee
Pan troglodytes
XP_001157639
909
105673
Y245
I
L
N
F
R
K
G
Y
R
R
N
D
K
Q
L
Rhesus Macaque
Macaca mulatta
XP_001100012
907
105697
Y245
I
L
N
F
R
K
G
Y
R
R
N
D
K
Q
L
Dog
Lupus familis
XP_545549
908
105482
Y245
I
L
N
F
R
K
G
Y
R
R
N
D
K
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8C5N3
908
104755
Y243
I
L
N
F
R
K
G
Y
R
R
N
D
K
Q
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515527
921
106628
Y253
I
L
N
F
R
K
G
Y
R
R
N
D
K
Q
L
Chicken
Gallus gallus
Q5ZKA3
926
108657
Y251
I
L
N
F
R
K
G
Y
R
R
N
D
K
Q
L
Frog
Xenopus laevis
Q52KN9
803
92701
K211
M
S
W
E
A
L
K
K
S
I
N
G
L
V
N
Zebra Danio
Brachydanio rerio
Q08C72
985
113331
Y339
I
L
N
F
R
K
G
Y
R
R
N
D
K
Q
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VJ87
1330
151618
F502
V
I
Q
F
R
R
A
F
R
R
N
D
K
M
V
Honey Bee
Apis mellifera
XP_001120152
706
80124
V114
E
L
L
K
E
N
I
V
R
G
R
G
L
L
A
Nematode Worm
Caenorhab. elegans
Q17336
897
104250
F276
I
V
Q
F
K
R
S
F
R
R
N
D
R
G
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53333
577
67276
Red Bread Mold
Neurospora crassa
Q7RX84
1010
113982
F304
V
L
R
F
R
K
A
F
K
R
N
D
K
A
V
Conservation
Percent
Protein Identity:
100
99.2
97.2
93.2
N.A.
84.2
N.A.
N.A.
77.5
70.6
67.1
60.9
N.A.
39.8
45.5
45.9
N.A.
Protein Similarity:
100
99.4
98.4
95.6
N.A.
90
N.A.
N.A.
86.5
80.2
74.6
71.8
N.A.
52.1
58.9
65.7
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
100
100
6.6
93.3
N.A.
46.6
13.3
40
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
100
100
13.3
93.3
N.A.
80
13.3
80
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.2
38.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.9
55.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
53.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
80
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
15
0
0
0
0
0
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
79
0
0
0
% D
% Glu:
8
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
79
0
0
0
22
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
58
0
0
8
0
15
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
65
8
0
0
0
0
8
0
0
8
0
0
0
0
0
% I
% Lys:
0
0
0
8
8
65
8
8
8
0
0
0
72
0
0
% K
% Leu:
0
72
8
0
0
8
0
0
0
0
0
0
15
8
50
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
58
0
0
8
0
0
0
0
86
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
15
0
0
0
0
0
0
0
0
0
0
58
8
% Q
% Arg:
0
0
8
0
72
15
0
0
79
79
8
0
8
0
0
% R
% Ser:
0
8
0
0
0
0
8
0
8
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
15
8
0
0
0
0
0
8
0
0
0
0
0
8
22
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
58
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _