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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CWC22
All Species:
21.82
Human Site:
Y871
Identified Species:
36.92
UniProt:
Q9HCG8
Number Species:
13
Phosphosite Substitution
Charge Score:
0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCG8
NP_065994.1
908
105535
Y871
S
R
S
D
E
D
R
Y
Q
N
G
A
E
R
R
Chimpanzee
Pan troglodytes
XP_001157639
909
105673
Y872
S
R
S
D
E
D
R
Y
Q
N
G
A
E
R
R
Rhesus Macaque
Macaca mulatta
XP_001100012
907
105697
Y870
S
R
S
D
E
D
R
Y
Q
N
G
A
E
R
R
Dog
Lupus familis
XP_545549
908
105482
Y870
S
R
S
D
E
D
R
Y
Q
N
G
A
E
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8C5N3
908
104755
C871
H
K
G
D
D
A
R
C
Q
N
S
A
E
R
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515527
921
106628
Y884
P
Q
G
E
E
D
R
Y
R
N
G
S
E
R
R
Chicken
Gallus gallus
Q5ZKA3
926
108657
Y889
E
E
E
D
D
H
R
Y
R
N
G
S
E
R
L
Frog
Xenopus laevis
Q52KN9
803
92701
S767
R
E
A
H
K
A
A
S
K
K
Q
A
P
D
D
Zebra Danio
Brachydanio rerio
Q08C72
985
113331
E949
S
R
E
R
S
R
K
E
M
D
S
R
D
S
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VJ87
1330
151618
D1250
S
D
R
G
E
R
S
D
R
G
E
R
S
D
R
Honey Bee
Apis mellifera
XP_001120152
706
80124
D670
V
I
V
N
D
G
N
D
D
S
V
V
T
V
A
Nematode Worm
Caenorhab. elegans
Q17336
897
104250
D858
D
R
S
K
D
R
E
D
R
R
D
R
R
R
H
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53333
577
67276
P541
E
N
S
R
S
R
S
P
F
T
V
E
T
R
K
Red Bread Mold
Neurospora crassa
Q7RX84
1010
113982
A957
S
P
P
P
L
A
D
A
A
T
G
S
R
R
V
Conservation
Percent
Protein Identity:
100
99.2
97.2
93.2
N.A.
84.2
N.A.
N.A.
77.5
70.6
67.1
60.9
N.A.
39.8
45.5
45.9
N.A.
Protein Similarity:
100
99.4
98.4
95.6
N.A.
90
N.A.
N.A.
86.5
80.2
74.6
71.8
N.A.
52.1
58.9
65.7
N.A.
P-Site Identity:
100
100
100
100
N.A.
53.3
N.A.
N.A.
60
46.6
6.6
13.3
N.A.
20
0
20
N.A.
P-Site Similarity:
100
100
100
100
N.A.
66.6
N.A.
N.A.
86.6
66.6
26.6
33.3
N.A.
26.6
20
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.2
38.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.9
55.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
22
8
8
8
0
0
43
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
43
29
36
8
22
8
8
8
0
8
15
8
% D
% Glu:
15
15
15
8
43
0
8
8
0
0
8
8
50
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
15
8
0
8
0
0
0
8
50
0
0
0
0
% G
% His:
8
0
0
8
0
8
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
8
8
0
8
0
8
8
0
0
0
0
8
% K
% Leu:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
8
0
8
0
0
8
0
0
50
0
0
0
0
0
% N
% Pro:
8
8
8
8
0
0
0
8
0
0
0
0
8
0
0
% P
% Gln:
0
8
0
0
0
0
0
0
36
0
8
0
0
0
0
% Q
% Arg:
8
43
8
15
0
29
50
0
29
8
0
22
15
72
50
% R
% Ser:
50
0
43
0
15
0
15
8
0
8
15
22
8
8
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
15
0
0
15
0
0
% T
% Val:
8
0
8
0
0
0
0
0
0
0
15
8
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
43
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _