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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SYTL2
All Species:
4.24
Human Site:
T148
Identified Species:
11.67
UniProt:
Q9HCH5
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCH5
NP_001156423.1
934
104930
T148
I
D
M
S
Q
E
N
T
R
K
P
N
V
S
P
Chimpanzee
Pan troglodytes
XP_001175288
934
105041
T148
I
D
M
S
Q
E
K
T
R
K
P
N
V
S
P
Rhesus Macaque
Macaca mulatta
XP_001100659
910
102141
N135
S
P
S
S
S
V
V
N
P
A
S
T
V
I
D
Dog
Lupus familis
XP_858503
932
104345
R147
I
D
T
R
E
N
T
R
K
S
T
V
S
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q99N50
950
106787
R148
D
M
S
Q
E
S
T
R
T
P
A
V
S
L
P
Rat
Rattus norvegicus
Q8VHQ7
672
75882
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512777
1943
213812
G150
G
L
D
V
P
E
D
G
T
S
R
T
A
V
S
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001088021
879
97854
W102
E
N
S
S
K
K
S
W
A
S
S
V
N
K
D
Zebra Danio
Brachydanio rerio
XP_691641
403
45858
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
90.7
87
N.A.
81.2
29.8
N.A.
31.8
N.A.
50.7
26.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
92.9
91.4
N.A.
87.6
46.2
N.A.
39.8
N.A.
66.3
34
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
13.3
13.3
N.A.
6.6
0
N.A.
6.6
N.A.
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
13.3
26.6
N.A.
13.3
0
N.A.
13.3
N.A.
33.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
12
12
12
0
12
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
34
12
0
0
0
12
0
0
0
0
0
0
0
23
% D
% Glu:
12
0
0
0
23
34
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
12
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
34
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% I
% Lys:
0
0
0
0
12
12
12
0
12
23
0
0
0
12
0
% K
% Leu:
0
12
0
0
0
0
0
0
0
0
0
0
0
12
0
% L
% Met:
0
12
23
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
12
0
0
0
12
12
12
0
0
0
23
12
0
0
% N
% Pro:
0
12
0
0
12
0
0
0
12
12
23
0
0
12
34
% P
% Gln:
0
0
0
12
23
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
12
0
0
0
23
23
0
12
0
0
0
0
% R
% Ser:
12
0
34
45
12
12
12
0
0
34
23
0
23
23
12
% S
% Thr:
0
0
12
0
0
0
23
23
23
0
12
23
0
0
0
% T
% Val:
0
0
0
12
0
12
12
0
0
0
0
34
34
12
0
% V
% Trp:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _