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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MSL2 All Species: 14.24
Human Site: T405 Identified Species: 44.76
UniProt: Q9HCI7 Number Species: 7
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HCI7 NP_001138889.1 577 62541 T405 S K T V L L S T K S M K K S H
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_542793 838 90536 T666 S K T V L L S T K S M K K S H
Cat Felis silvestris
Mouse Mus musculus Q69ZF8 577 62519 T405 S K T V L L S T K S M K K S H
Rat Rattus norvegicus XP_001071576 577 62434 T405 S K T V L L S T K S M K K S H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518890 532 56142 S373 L D H G P K K S H P K A K P G
Chicken Gallus gallus XP_426675 579 62234 L405 K I S K T V L L S N K S V K K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001156785 598 64113 P405 I P H M A V V P N G G G L P K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796886 364 40810 K205 K I K V K E R K L I K E Q A K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 68.1 N.A. 98.9 98.6 N.A. 74.6 83.9 N.A. 59.3 N.A. N.A. N.A. N.A. 20.1
Protein Similarity: 100 N.A. N.A. 68.3 N.A. 99.6 99.4 N.A. 82.5 91.5 N.A. 72.5 N.A. N.A. N.A. N.A. 33.2
P-Site Identity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 6.6 0 N.A. 0 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 13.3 20 N.A. 13.3 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 13 0 0 0 0 0 0 13 0 13 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 13 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 13 0 0 0 0 0 13 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 13 0 0 0 0 0 13 13 13 0 0 13 % G
% His: 0 0 25 0 0 0 0 0 13 0 0 0 0 0 50 % H
% Ile: 13 25 0 0 0 0 0 0 0 13 0 0 0 0 0 % I
% Lys: 25 50 13 13 13 13 13 13 50 0 38 50 63 13 38 % K
% Leu: 13 0 0 0 50 50 13 13 13 0 0 0 13 0 0 % L
% Met: 0 0 0 13 0 0 0 0 0 0 50 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 13 13 0 0 0 0 0 % N
% Pro: 0 13 0 0 13 0 0 13 0 13 0 0 0 25 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 13 0 0 % Q
% Arg: 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 % R
% Ser: 50 0 13 0 0 0 50 13 13 50 0 13 0 50 0 % S
% Thr: 0 0 50 0 13 0 0 50 0 0 0 0 0 0 0 % T
% Val: 0 0 0 63 0 25 13 0 0 0 0 0 13 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _