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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TNRC6C All Species: 18.18
Human Site: S874 Identified Species: 50
UniProt: Q9HCJ0 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HCJ0 NP_001136112.1 1690 175964 S874 L C K P A S K S M Q E G W G S
Chimpanzee Pan troglodytes XP_001144739 1004 106477 N242 A L K S N N M N L D Q A M S A
Rhesus Macaque Macaca mulatta XP_001104782 1982 207001 S1127 L C K P A S K S M Q E G W G S
Dog Lupus familis XP_540459 2091 217385 S1239 L C K P A S K S M Q E G W G S
Cat Felis silvestris
Mouse Mus musculus Q3UHC0 1690 175756 S869 L C K P A S K S M Q E G W G S
Rat Rattus norvegicus NP_001101019 1954 209814 G1111 G E D T P L P G S R P T G W E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517138 1197 124906 K435 K G M K T S S K Q D E A W I M
Chicken Gallus gallus XP_415612 1886 197024 S1065 L C K P A S K S M Q E G W G S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_689365 1881 197727 P1056 S A P C K P A P K S M Q D S W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 57 84.3 74.2 N.A. 91 33.3 N.A. 58.2 79.7 N.A. 50.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 57 84.6 76.9 N.A. 94 46.1 N.A. 62.7 83.9 N.A. 61.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 100 100 N.A. 100 0 N.A. 20 100 N.A. 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 40 100 100 N.A. 100 6.6 N.A. 20 100 N.A. 0 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 12 0 0 56 0 12 0 0 0 0 23 0 0 12 % A
% Cys: 0 56 0 12 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 12 0 0 0 0 0 0 23 0 0 12 0 0 % D
% Glu: 0 12 0 0 0 0 0 0 0 0 67 0 0 0 12 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 12 12 0 0 0 0 0 12 0 0 0 56 12 56 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % I
% Lys: 12 0 67 12 12 0 56 12 12 0 0 0 0 0 0 % K
% Leu: 56 12 0 0 0 12 0 0 12 0 0 0 0 0 0 % L
% Met: 0 0 12 0 0 0 12 0 56 0 12 0 12 0 12 % M
% Asn: 0 0 0 0 12 12 0 12 0 0 0 0 0 0 0 % N
% Pro: 0 0 12 56 12 12 12 12 0 0 12 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 12 56 12 12 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % R
% Ser: 12 0 0 12 0 67 12 56 12 12 0 0 0 23 56 % S
% Thr: 0 0 0 12 12 0 0 0 0 0 0 12 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 67 12 12 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _