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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRRC4C
All Species:
22.12
Human Site:
T435
Identified Species:
69.52
UniProt:
Q9HCJ2
Number Species:
7
Phosphosite Substitution
Charge Score:
0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCJ2
NP_065980.1
640
71950
T435
V
S
N
S
V
G
N
T
T
A
S
A
T
L
N
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001116118
713
76269
T445
V
T
N
S
A
G
N
T
T
A
S
A
T
L
N
Dog
Lupus familis
XP_540535
639
71844
T435
V
S
N
S
V
G
N
T
T
A
S
A
T
L
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8C031
640
71973
T435
V
S
N
S
V
G
N
T
T
A
S
A
T
L
N
Rat
Rattus norvegicus
P0CC10
709
76100
T447
V
T
N
S
A
G
N
T
T
A
S
A
T
L
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509222
640
71932
T435
V
S
N
S
V
G
N
T
T
A
S
A
T
L
N
Chicken
Gallus gallus
Q50L44
613
69561
D405
K
E
F
K
D
F
P
D
V
L
L
P
N
Y
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q66HV9
622
70428
D414
K
E
F
K
D
F
P
D
V
L
P
P
N
Y
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
58.7
99.6
N.A.
99.6
58.8
N.A.
96.8
23.2
N.A.
21.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
71.9
99.8
N.A.
100
72
N.A.
99
38.7
N.A.
38.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
86.6
100
N.A.
100
86.6
N.A.
100
0
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
93.3
100
N.A.
100
93.3
N.A.
100
0
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
25
0
0
0
0
75
0
75
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
25
0
0
25
0
0
0
0
0
0
0
% D
% Glu:
0
25
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
25
0
0
25
0
0
0
0
0
0
0
0
25
% F
% Gly:
0
0
0
0
0
75
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
25
0
0
25
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
25
13
0
0
75
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
75
0
0
0
75
0
0
0
0
0
25
0
75
% N
% Pro:
0
0
0
0
0
0
25
0
0
0
13
25
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
50
0
75
0
0
0
0
0
0
75
0
0
0
0
% S
% Thr:
0
25
0
0
0
0
0
75
75
0
0
0
75
0
0
% T
% Val:
75
0
0
0
50
0
0
0
25
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
25
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _