KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZSWIM6
All Species:
6.06
Human Site:
Y543
Identified Species:
13.33
UniProt:
Q9HCJ5
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCJ5
NP_065979.1
1215
133470
Y543
S
S
D
L
Y
T
N
Y
C
Y
H
D
D
T
E
Chimpanzee
Pan troglodytes
XP_513126
1395
153015
P726
S
S
D
V
Y
T
A
P
A
C
Q
R
E
S
E
Rhesus Macaque
Macaca mulatta
XP_001094447
1002
112341
P350
L
F
N
S
Q
G
Q
P
L
W
L
E
H
V
P
Dog
Lupus familis
XP_853236
1229
135332
P560
S
S
D
I
Y
T
A
P
A
C
Q
Q
E
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q80TB7
1017
114983
H365
S
R
G
W
P
L
W
H
E
H
V
P
T
A
C
Rat
Rattus norvegicus
NP_001041349
793
89869
H141
S
R
G
W
P
L
W
H
E
H
V
P
T
A
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507506
824
90485
C172
A
S
I
D
D
E
N
C
W
H
L
D
E
E
Q
Chicken
Gallus gallus
XP_422431
1110
122366
S449
A
Y
Q
R
E
G
E
S
L
L
F
N
S
Q
G
Frog
Xenopus laevis
NP_001090431
1092
121735
D440
G
R
P
L
W
L
G
D
H
F
P
V
A
C
A
Zebra Danio
Brachydanio rerio
NP_001129959
1132
127206
Y460
S
D
D
L
Y
T
N
Y
C
Y
H
E
H
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789113
983
110838
S331
D
Y
G
L
F
N
Q
S
A
F
P
L
W
S
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.2
64.1
67.6
N.A.
82.2
63.6
N.A.
46.3
69.6
57.4
80.3
N.A.
N.A.
N.A.
N.A.
50.2
Protein Similarity:
100
71.6
73
78.4
N.A.
83
64.5
N.A.
53.4
78
71.9
87
N.A.
N.A.
N.A.
N.A.
62.3
P-Site Identity:
100
40
0
40
N.A.
6.6
6.6
N.A.
20
0
6.6
80
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
60
20
60
N.A.
20
20
N.A.
46.6
13.3
20
86.6
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
0
0
0
0
19
0
28
0
0
0
10
19
10
% A
% Cys:
0
0
0
0
0
0
0
10
19
19
0
0
0
10
19
% C
% Asp:
10
10
37
10
10
0
0
10
0
0
0
19
10
0
0
% D
% Glu:
0
0
0
0
10
10
10
0
19
0
0
19
28
10
46
% E
% Phe:
0
10
0
0
10
0
0
0
0
19
10
0
0
0
0
% F
% Gly:
10
0
28
0
0
19
10
0
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
19
10
28
19
0
19
0
0
% H
% Ile:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
0
0
37
0
28
0
0
19
10
19
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
10
28
0
0
0
0
10
0
0
0
% N
% Pro:
0
0
10
0
19
0
0
28
0
0
19
19
0
0
10
% P
% Gln:
0
0
10
0
10
0
19
0
0
0
19
10
0
10
10
% Q
% Arg:
0
28
0
10
0
0
0
0
0
0
0
10
0
0
0
% R
% Ser:
55
37
0
10
0
0
0
19
0
0
0
0
10
28
0
% S
% Thr:
0
0
0
0
0
37
0
0
0
0
0
0
19
19
0
% T
% Val:
0
0
0
10
0
0
0
0
0
0
19
10
0
10
0
% V
% Trp:
0
0
0
19
10
0
19
0
10
10
0
0
10
0
0
% W
% Tyr:
0
19
0
0
37
0
0
19
0
19
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _