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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZSWIM6
All Species:
8.48
Human Site:
Y786
Identified Species:
18.67
UniProt:
Q9HCJ5
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCJ5
NP_065979.1
1215
133470
Y786
P
H
D
A
E
L
A
Y
K
I
A
L
R
A
M
Chimpanzee
Pan troglodytes
XP_513126
1395
153015
Y966
P
H
D
P
D
L
S
Y
K
L
A
L
R
A
M
Rhesus Macaque
Macaca mulatta
XP_001094447
1002
112341
V584
L
R
A
M
R
L
P
V
L
E
N
S
A
S
A
Dog
Lupus familis
XP_853236
1229
135332
Y800
P
H
D
P
D
L
S
Y
K
L
A
L
R
A
M
Cat
Felis silvestris
Mouse
Mus musculus
Q80TB7
1017
114983
V599
L
R
A
M
R
L
L
V
L
E
S
T
A
P
T
Rat
Rattus norvegicus
NP_001041349
793
89869
V375
L
R
A
M
R
L
L
V
L
E
S
T
A
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507506
824
90485
V406
L
R
L
A
V
A
I
V
N
T
L
R
Q
Q
Q
Chicken
Gallus gallus
XP_422431
1110
122366
L683
D
A
D
L
A
Y
K
L
A
L
R
A
M
R
L
Frog
Xenopus laevis
NP_001090431
1092
121735
I674
R
L
P
V
L
E
S
I
L
P
P
H
G
S
D
Zebra Danio
Brachydanio rerio
NP_001129959
1132
127206
K703
H
D
A
E
L
A
Y
K
I
A
L
R
A
M
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789113
983
110838
L565
R
A
M
R
L
P
I
L
E
E
G
T
S
G
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.2
64.1
67.6
N.A.
82.2
63.6
N.A.
46.3
69.6
57.4
80.3
N.A.
N.A.
N.A.
N.A.
50.2
Protein Similarity:
100
71.6
73
78.4
N.A.
83
64.5
N.A.
53.4
78
71.9
87
N.A.
N.A.
N.A.
N.A.
62.3
P-Site Identity:
100
73.3
6.6
73.3
N.A.
6.6
6.6
N.A.
6.6
6.6
0
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
93.3
13.3
93.3
N.A.
13.3
13.3
N.A.
13.3
20
13.3
0
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
37
19
10
19
10
0
10
10
28
10
37
28
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
37
0
19
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
0
0
0
10
10
10
0
0
10
37
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
10
0
10
10
0
% G
% His:
10
28
0
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
0
0
0
0
0
19
10
10
10
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
10
10
28
0
0
0
0
0
0
% K
% Leu:
37
10
10
10
28
55
19
19
37
28
19
28
0
0
10
% L
% Met:
0
0
10
28
0
0
0
0
0
0
0
0
10
10
28
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% N
% Pro:
28
0
10
19
0
10
10
0
0
10
10
0
0
19
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
10
% Q
% Arg:
19
37
0
10
28
0
0
0
0
0
10
19
28
10
10
% R
% Ser:
0
0
0
0
0
0
28
0
0
0
19
10
10
19
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
10
0
28
0
0
19
% T
% Val:
0
0
0
10
10
0
0
37
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
10
28
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _