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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ROBO2
All Species:
18.48
Human Site:
T581
Identified Species:
58.1
UniProt:
Q9HCK4
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCK4
NP_002933.1
1378
151200
T581
H
V
K
T
T
L
Y
T
V
R
G
L
R
P
N
Chimpanzee
Pan troglodytes
XP_001144482
1395
153226
T598
H
V
K
T
T
L
Y
T
V
R
G
L
R
P
N
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_544815
1378
151004
T581
H
V
K
T
T
L
Y
T
V
R
G
L
R
P
N
Cat
Felis silvestris
Mouse
Mus musculus
Q7TPD3
1470
161171
T585
H
V
K
T
T
L
Y
T
V
R
G
L
R
P
N
Rat
Rattus norvegicus
O55005
1651
180729
T618
A
E
N
V
K
T
E
T
F
A
I
K
G
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512208
1575
172904
T577
H
V
K
T
T
L
F
T
V
R
G
L
R
P
N
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001164069
1396
153618
K591
A
D
S
V
K
V
E
K
H
T
V
V
G
L
N
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O97394
2224
246236
I715
V
S
A
D
Q
R
W
I
L
L
E
N
L
K
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.7
N.A.
97.7
N.A.
89.8
48
N.A.
79.5
N.A.
53.5
N.A.
N.A.
20.2
N.A.
N.A.
N.A.
Protein Similarity:
100
98.2
N.A.
98.6
N.A.
91.6
60.7
N.A.
82.9
N.A.
66.6
N.A.
N.A.
32.9
N.A.
N.A.
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
100
6.6
N.A.
93.3
N.A.
6.6
N.A.
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
6.6
N.A.
100
N.A.
20
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
0
13
0
0
0
0
0
0
13
0
0
0
0
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
13
0
13
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
13
0
0
0
0
25
0
0
0
13
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
13
0
13
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
63
0
25
0
0
% G
% His:
63
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
13
0
0
13
0
0
0
0
% I
% Lys:
0
0
63
0
25
0
0
13
0
0
0
13
0
13
13
% K
% Leu:
0
0
0
0
0
63
0
0
13
13
0
63
13
25
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
13
0
0
0
0
0
0
0
0
13
0
0
75
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
63
0
% P
% Gln:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
13
0
0
0
63
0
0
63
0
0
% R
% Ser:
0
13
13
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
63
63
13
0
75
0
13
0
0
0
0
0
% T
% Val:
13
63
0
25
0
13
0
0
63
0
13
13
0
0
0
% V
% Trp:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
50
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _