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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHD8
All Species:
26.06
Human Site:
S1286
Identified Species:
47.78
UniProt:
Q9HCK8
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCK8
NP_065971.2
2581
290518
S1286
K
A
V
L
Q
S
M
S
G
R
D
G
N
I
T
Chimpanzee
Pan troglodytes
XP_001153522
2556
287735
S1261
K
A
V
L
Q
S
M
S
G
R
D
G
N
I
T
Rhesus Macaque
Macaca mulatta
XP_001096619
2585
291342
S1291
K
A
V
L
Q
S
M
S
G
R
D
G
N
I
T
Dog
Lupus familis
XP_532624
2304
262413
E1171
R
T
D
C
F
R
V
E
K
H
L
L
V
Y
G
Cat
Felis silvestris
Mouse
Mus musculus
Q09XV5
2582
290829
S1288
K
A
V
L
Q
S
M
S
G
R
D
G
N
I
T
Rat
Rattus norvegicus
Q9JIX5
2581
290674
S1286
K
A
V
L
Q
S
M
S
G
R
D
G
N
I
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512847
2876
321833
S1335
K
A
V
L
Q
S
M
S
G
R
E
S
S
I
G
Chicken
Gallus gallus
Q06A37
3011
338194
S1444
K
A
V
L
Q
S
M
S
G
R
E
N
A
T
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
B0R0I6
2511
279693
S1321
L
D
R
A
V
L
Q
S
M
S
G
N
K
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KU24
1883
211809
A809
L
K
K
C
C
N
H
A
A
L
I
R
P
S
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22516
1787
205237
F713
I
R
E
H
E
F
S
F
V
D
G
A
V
R
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S775
1384
158387
A310
G
K
T
I
Q
S
I
A
L
L
A
S
L
F
E
Baker's Yeast
Sacchar. cerevisiae
P32657
1468
168223
G394
M
A
F
L
W
S
K
G
D
N
G
I
L
A
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
97
87.8
N.A.
96.1
96.3
N.A.
48.5
43.4
N.A.
56.7
N.A.
23.9
N.A.
23
N.A.
Protein Similarity:
100
98.9
97.5
88.3
N.A.
97.8
97.8
N.A.
62
57
N.A.
68.6
N.A.
39.3
N.A.
37.6
N.A.
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
73.3
66.6
N.A.
6.6
N.A.
0
N.A.
0
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
86.6
73.3
N.A.
13.3
N.A.
13.3
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.9
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34.3
36
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
62
0
8
0
0
0
16
8
0
8
8
8
8
0
% A
% Cys:
0
0
0
16
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
0
0
0
0
0
8
8
39
0
0
0
8
% D
% Glu:
0
0
8
0
8
0
0
8
0
0
16
0
0
8
16
% E
% Phe:
0
0
8
0
8
8
0
8
0
0
0
0
0
8
0
% F
% Gly:
8
0
0
0
0
0
0
8
54
0
24
39
0
0
24
% G
% His:
0
0
0
8
0
0
8
0
0
8
0
0
0
0
0
% H
% Ile:
8
0
0
8
0
0
8
0
0
0
8
8
0
47
0
% I
% Lys:
54
16
8
0
0
0
8
0
8
0
0
0
8
0
0
% K
% Leu:
16
0
0
62
0
8
0
0
8
16
8
8
16
0
0
% L
% Met:
8
0
0
0
0
0
54
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
8
0
16
39
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
0
0
0
0
62
0
8
0
0
0
0
0
0
0
0
% Q
% Arg:
8
8
8
0
0
8
0
0
0
54
0
8
0
8
0
% R
% Ser:
0
0
0
0
0
70
8
62
0
8
0
16
8
8
8
% S
% Thr:
0
8
8
0
0
0
0
0
0
0
0
0
0
8
39
% T
% Val:
0
0
54
0
8
0
8
0
8
0
0
0
16
0
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _