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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHD8
All Species:
32.12
Human Site:
S1356
Identified Species:
58.89
UniProt:
Q9HCK8
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCK8
NP_065971.2
2581
290518
S1356
G
S
T
F
A
K
A
S
F
V
A
S
E
N
R
Chimpanzee
Pan troglodytes
XP_001153522
2556
287735
S1331
G
S
T
F
A
K
A
S
F
V
A
S
E
N
R
Rhesus Macaque
Macaca mulatta
XP_001096619
2585
291342
S1361
G
S
T
F
A
K
A
S
F
V
A
S
E
N
R
Dog
Lupus familis
XP_532624
2304
262413
Q1241
N
G
K
T
K
E
L
Q
N
H
S
G
L
S
I
Cat
Felis silvestris
Mouse
Mus musculus
Q09XV5
2582
290829
S1358
G
S
T
F
A
K
A
S
F
V
A
S
E
N
R
Rat
Rattus norvegicus
Q9JIX5
2581
290674
S1356
G
S
T
F
A
K
A
S
F
V
A
S
E
N
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512847
2876
321833
S1405
G
S
T
F
A
K
A
S
F
V
A
S
G
N
R
Chicken
Gallus gallus
Q06A37
3011
338194
S1514
G
S
T
F
A
K
A
S
F
V
A
S
G
N
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
B0R0I6
2511
279693
S1391
G
S
T
F
S
K
A
S
F
V
A
S
E
N
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KU24
1883
211809
F879
L
Q
K
R
H
F
P
F
Q
R
L
D
G
S
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22516
1787
205237
N783
F
K
N
L
R
E
Y
N
I
Q
Y
R
V
L
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S775
1384
158387
S380
K
K
I
K
K
K
K
S
G
Q
I
S
S
E
S
Baker's Yeast
Sacchar. cerevisiae
P32657
1468
168223
D464
M
G
N
Q
K
S
R
D
T
I
R
E
Y
E
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
97
87.8
N.A.
96.1
96.3
N.A.
48.5
43.4
N.A.
56.7
N.A.
23.9
N.A.
23
N.A.
Protein Similarity:
100
98.9
97.5
88.3
N.A.
97.8
97.8
N.A.
62
57
N.A.
68.6
N.A.
39.3
N.A.
37.6
N.A.
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
93.3
93.3
N.A.
93.3
N.A.
0
N.A.
0
N.A.
P-Site Similarity:
100
100
100
20
N.A.
100
100
N.A.
93.3
93.3
N.A.
100
N.A.
6.6
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.9
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34.3
36
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
54
0
62
0
0
0
62
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% D
% Glu:
0
0
0
0
0
16
0
0
0
0
0
8
47
16
0
% E
% Phe:
8
0
0
62
0
8
0
8
62
0
0
0
0
0
8
% F
% Gly:
62
16
0
0
0
0
0
0
8
0
0
8
24
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
8
8
8
0
0
0
16
% I
% Lys:
8
16
16
8
24
70
8
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
0
8
0
0
8
0
0
0
8
0
8
8
8
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
16
0
0
0
0
8
8
0
0
0
0
62
0
% N
% Pro:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
8
0
0
0
8
8
16
0
0
0
0
0
% Q
% Arg:
0
0
0
8
8
0
8
0
0
8
8
8
0
0
62
% R
% Ser:
0
62
0
0
8
8
0
70
0
0
8
70
8
16
8
% S
% Thr:
0
0
62
8
0
0
0
0
8
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
62
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
8
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _