KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHD8
All Species:
21.52
Human Site:
S1542
Identified Species:
39.44
UniProt:
Q9HCK8
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCK8
NP_065971.2
2581
290518
S1542
G
K
K
V
K
S
Q
S
T
F
D
I
H
K
A
Chimpanzee
Pan troglodytes
XP_001153522
2556
287735
S1517
G
K
K
V
K
S
Q
S
T
F
D
I
H
K
A
Rhesus Macaque
Macaca mulatta
XP_001096619
2585
291342
S1547
G
K
K
V
K
S
Q
S
T
F
D
I
H
K
A
Dog
Lupus familis
XP_532624
2304
262413
P1419
C
E
D
P
E
Y
K
P
L
Q
G
P
P
K
D
Cat
Felis silvestris
Mouse
Mus musculus
Q09XV5
2582
290829
S1544
G
K
K
V
K
S
Q
S
T
F
D
I
H
K
A
Rat
Rattus norvegicus
Q9JIX5
2581
290674
S1542
G
K
K
V
K
S
Q
S
T
F
D
I
H
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512847
2876
321833
A1591
G
K
K
V
K
T
Q
A
S
T
F
D
I
H
K
Chicken
Gallus gallus
Q06A37
3011
338194
S1703
G
K
K
V
K
A
Q
S
S
Q
P
M
L
Q
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
B0R0I6
2511
279693
Q1585
K
G
K
R
V
K
A
Q
S
S
F
D
V
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KU24
1883
211809
M1057
T
R
N
E
D
P
E
M
P
A
D
D
L
L
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22516
1787
205237
I961
D
G
G
H
R
V
L
I
F
S
Q
M
T
M
M
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S775
1384
158387
N558
G
A
Q
I
S
L
N
N
I
M
M
E
L
R
K
Baker's Yeast
Sacchar. cerevisiae
P32657
1468
168223
K642
S
A
L
T
A
G
A
K
G
G
H
F
S
L
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
97
87.8
N.A.
96.1
96.3
N.A.
48.5
43.4
N.A.
56.7
N.A.
23.9
N.A.
23
N.A.
Protein Similarity:
100
98.9
97.5
88.3
N.A.
97.8
97.8
N.A.
62
57
N.A.
68.6
N.A.
39.3
N.A.
37.6
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
100
100
N.A.
40
46.6
N.A.
6.6
N.A.
6.6
N.A.
0
N.A.
P-Site Similarity:
100
100
100
26.6
N.A.
100
100
N.A.
60
73.3
N.A.
20
N.A.
26.6
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.9
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34.3
36
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
0
8
8
16
8
0
8
0
0
0
0
39
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
0
8
0
0
0
0
0
47
24
0
0
16
% D
% Glu:
0
8
0
8
8
0
8
0
0
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
39
16
8
0
0
0
% F
% Gly:
62
16
8
0
0
8
0
0
8
8
8
0
0
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
8
0
39
8
0
% H
% Ile:
0
0
0
8
0
0
0
8
8
0
0
39
8
0
0
% I
% Lys:
8
54
62
0
54
8
8
8
0
0
0
0
0
47
24
% K
% Leu:
0
0
8
0
0
8
8
0
8
0
0
0
24
16
8
% L
% Met:
0
0
0
0
0
0
0
8
0
8
8
16
0
8
8
% M
% Asn:
0
0
8
0
0
0
8
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
8
0
8
0
8
8
0
8
8
8
0
0
% P
% Gln:
0
0
8
0
0
0
54
8
0
16
8
0
0
16
0
% Q
% Arg:
0
8
0
8
8
0
0
0
0
0
0
0
0
8
0
% R
% Ser:
8
0
0
0
8
39
0
47
24
16
0
0
8
0
8
% S
% Thr:
8
0
0
8
0
8
0
0
39
8
0
0
8
0
0
% T
% Val:
0
0
0
54
8
8
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _