KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHD8
All Species:
23.64
Human Site:
S1627
Identified Species:
43.33
UniProt:
Q9HCK8
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCK8
NP_065971.2
2581
290518
S1627
V
P
T
T
W
W
D
S
E
A
D
K
S
L
L
Chimpanzee
Pan troglodytes
XP_001153522
2556
287735
S1602
V
P
T
T
W
W
D
S
E
A
D
K
S
L
L
Rhesus Macaque
Macaca mulatta
XP_001096619
2585
291342
S1632
V
P
T
T
W
W
D
S
E
A
D
K
S
L
L
Dog
Lupus familis
XP_532624
2304
262413
D1495
I
E
A
A
E
R
G
D
R
R
R
R
R
C
E
Cat
Felis silvestris
Mouse
Mus musculus
Q09XV5
2582
290829
S1629
V
P
T
T
W
W
D
S
E
A
D
K
S
L
L
Rat
Rattus norvegicus
Q9JIX5
2581
290674
S1627
V
P
T
T
W
W
D
S
E
A
D
K
S
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512847
2876
321833
T1677
V
P
A
E
W
W
D
T
D
A
D
K
S
L
L
Chicken
Gallus gallus
Q06A37
3011
338194
K1789
V
P
A
D
W
W
D
K
E
A
D
K
S
L
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
B0R0I6
2511
279693
A1671
V
P
S
G
W
W
D
A
E
A
D
R
C
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KU24
1883
211809
A1132
L
P
P
R
R
K
T
A
A
N
Q
N
E
G
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22516
1787
205237
S1036
D
T
V
I
I
Y
D
S
D
W
N
P
H
N
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S775
1384
158387
H633
L
L
E
D
Y
C
T
H
K
K
W
Q
Y
E
R
Baker's Yeast
Sacchar. cerevisiae
P32657
1468
168223
F717
D
G
H
R
V
L
I
F
S
Q
M
V
R
M
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
97
87.8
N.A.
96.1
96.3
N.A.
48.5
43.4
N.A.
56.7
N.A.
23.9
N.A.
23
N.A.
Protein Similarity:
100
98.9
97.5
88.3
N.A.
97.8
97.8
N.A.
62
57
N.A.
68.6
N.A.
39.3
N.A.
37.6
N.A.
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
73.3
80
N.A.
66.6
N.A.
6.6
N.A.
13.3
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
86.6
80
N.A.
86.6
N.A.
20
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.9
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34.3
36
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
24
8
0
0
0
16
8
62
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
8
8
0
% C
% Asp:
16
0
0
16
0
0
70
8
16
0
62
0
0
0
8
% D
% Glu:
0
8
8
8
8
0
0
0
54
0
0
0
8
8
8
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
8
0
0
8
0
0
0
0
0
0
8
0
% G
% His:
0
0
8
0
0
0
0
8
0
0
0
0
8
0
0
% H
% Ile:
8
0
0
8
8
0
8
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
8
0
8
8
8
0
54
0
0
8
% K
% Leu:
16
8
0
0
0
8
0
0
0
0
0
0
0
62
70
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
8
8
0
8
0
% N
% Pro:
0
70
8
0
0
0
0
0
0
0
0
8
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
8
8
0
0
0
% Q
% Arg:
0
0
0
16
8
8
0
0
8
8
8
16
16
0
8
% R
% Ser:
0
0
8
0
0
0
0
47
8
0
0
0
54
0
0
% S
% Thr:
0
8
39
39
0
0
16
8
0
0
0
0
0
0
0
% T
% Val:
62
0
8
0
8
0
0
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
62
62
0
0
0
8
8
0
0
0
0
% W
% Tyr:
0
0
0
0
8
8
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _