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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHD8
All Species:
19.09
Human Site:
S2091
Identified Species:
35
UniProt:
Q9HCK8
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCK8
NP_065971.2
2581
290518
S2091
S
S
S
S
S
S
S
S
S
S
S
T
D
E
S
Chimpanzee
Pan troglodytes
XP_001153522
2556
287735
S2066
S
S
S
S
S
S
S
S
S
S
S
T
D
E
S
Rhesus Macaque
Macaca mulatta
XP_001096619
2585
291342
S2096
S
S
S
S
S
S
S
S
S
S
S
T
D
E
S
Dog
Lupus familis
XP_532624
2304
262413
Q1849
L
L
S
L
T
M
S
Q
D
G
F
P
N
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q09XV5
2582
290829
S2093
S
S
S
S
S
S
S
S
S
S
T
D
E
S
E
Rat
Rattus norvegicus
Q9JIX5
2581
290674
S2091
S
S
S
S
S
S
S
S
S
S
S
D
E
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512847
2876
321833
S2128
Q
R
V
S
K
R
G
S
E
S
S
S
D
S
D
Chicken
Gallus gallus
Q06A37
3011
338194
Q2258
D
K
S
E
E
S
S
Q
P
E
A
G
A
V
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
B0R0I6
2511
279693
N2088
W
V
W
K
K
S
K
N
N
G
P
S
E
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KU24
1883
211809
N1485
S
A
S
D
N
N
G
N
K
P
M
H
F
T
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22516
1787
205237
A1389
R
E
G
L
N
R
Q
A
V
L
S
R
I
G
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S775
1384
158387
T986
V
P
R
L
K
Q
K
T
F
E
E
I
N
E
Y
Baker's Yeast
Sacchar. cerevisiae
P32657
1468
168223
N1070
C
V
H
E
E
E
K
N
R
K
E
I
L
E
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
97
87.8
N.A.
96.1
96.3
N.A.
48.5
43.4
N.A.
56.7
N.A.
23.9
N.A.
23
N.A.
Protein Similarity:
100
98.9
97.5
88.3
N.A.
97.8
97.8
N.A.
62
57
N.A.
68.6
N.A.
39.3
N.A.
37.6
N.A.
P-Site Identity:
100
100
100
20
N.A.
66.6
73.3
N.A.
33.3
26.6
N.A.
6.6
N.A.
13.3
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
33.3
N.A.
80
80
N.A.
40
33.3
N.A.
33.3
N.A.
46.6
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.9
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34.3
36
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
8
0
0
8
0
8
0
8
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
8
0
0
0
0
8
0
0
16
31
0
16
% D
% Glu:
0
8
0
16
16
8
0
0
8
16
16
0
24
47
16
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
8
0
8
0
0
% F
% Gly:
0
0
8
0
0
0
16
0
0
16
0
8
0
8
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
16
8
0
0
% I
% Lys:
0
8
0
8
24
0
24
0
8
8
0
0
0
0
16
% K
% Leu:
8
8
0
24
0
0
0
0
0
8
0
0
8
0
8
% L
% Met:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
16
8
0
24
8
0
0
0
16
0
0
% N
% Pro:
0
8
0
0
0
0
0
0
8
8
8
8
0
0
0
% P
% Gln:
8
0
0
0
0
8
8
16
0
0
0
0
0
0
0
% Q
% Arg:
8
8
8
0
0
16
0
0
8
0
0
8
0
8
0
% R
% Ser:
47
39
62
47
39
54
54
47
39
47
47
16
0
24
31
% S
% Thr:
0
0
0
0
8
0
0
8
0
0
8
24
0
8
0
% T
% Val:
8
16
8
0
0
0
0
0
8
0
0
0
0
8
0
% V
% Trp:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _