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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHD8
All Species:
19.09
Human Site:
S2119
Identified Species:
35
UniProt:
Q9HCK8
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCK8
NP_065971.2
2581
290518
S2119
S
K
L
Y
D
E
E
S
L
L
S
L
T
M
S
Chimpanzee
Pan troglodytes
XP_001153522
2556
287735
S2094
S
K
L
Y
D
E
E
S
L
L
S
L
T
M
S
Rhesus Macaque
Macaca mulatta
XP_001096619
2585
291342
S2124
S
K
L
Y
D
E
E
S
L
L
S
L
T
M
S
Dog
Lupus familis
XP_532624
2304
262413
P1877
R
Q
R
A
S
E
W
P
K
D
R
V
L
I
N
Cat
Felis silvestris
Mouse
Mus musculus
Q09XV5
2582
290829
S2121
P
K
L
Y
D
E
E
S
L
L
S
L
T
M
S
Rat
Rattus norvegicus
Q9JIX5
2581
290674
S2119
P
K
L
Y
D
E
E
S
L
L
S
L
T
M
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512847
2876
321833
S2156
S
S
S
S
S
S
S
S
S
S
C
S
H
S
R
Chicken
Gallus gallus
Q06A37
3011
338194
R2286
S
T
A
R
D
E
T
R
D
G
F
Y
M
E
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
B0R0I6
2511
279693
S2116
D
S
D
S
G
S
S
S
S
S
R
H
S
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KU24
1883
211809
C1513
D
P
S
I
F
N
E
C
K
E
K
M
R
P
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22516
1787
205237
P1417
F
N
G
E
W
S
M
P
E
T
R
E
K
M
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S775
1384
158387
D1014
E
N
S
P
T
F
S
D
G
V
P
K
E
G
L
Baker's Yeast
Sacchar. cerevisiae
P32657
1468
168223
N1098
S
G
E
I
K
A
E
N
Q
P
K
D
N
P
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
97
87.8
N.A.
96.1
96.3
N.A.
48.5
43.4
N.A.
56.7
N.A.
23.9
N.A.
23
N.A.
Protein Similarity:
100
98.9
97.5
88.3
N.A.
97.8
97.8
N.A.
62
57
N.A.
68.6
N.A.
39.3
N.A.
37.6
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
93.3
93.3
N.A.
13.3
20
N.A.
13.3
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
33.3
N.A.
93.3
93.3
N.A.
13.3
20
N.A.
20
N.A.
13.3
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.9
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34.3
36
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
0
8
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% C
% Asp:
16
0
8
0
47
0
0
8
8
8
0
8
0
0
8
% D
% Glu:
8
0
8
8
0
54
54
0
8
8
0
8
8
8
0
% E
% Phe:
8
0
0
0
8
8
0
0
0
0
8
0
0
0
0
% F
% Gly:
0
8
8
0
8
0
0
0
8
8
0
0
0
16
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% H
% Ile:
0
0
0
16
0
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
0
39
0
0
8
0
0
0
16
0
16
8
8
0
0
% K
% Leu:
0
0
39
0
0
0
0
0
39
39
0
39
8
0
24
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
8
8
47
0
% M
% Asn:
0
16
0
0
0
8
0
8
0
0
0
0
8
0
8
% N
% Pro:
16
8
0
8
0
0
0
16
0
8
8
0
0
16
0
% P
% Gln:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
8
0
8
8
0
0
0
8
0
0
24
0
8
0
8
% R
% Ser:
47
16
24
16
16
24
24
54
16
16
39
8
8
8
47
% S
% Thr:
0
8
0
0
8
0
8
0
0
8
0
0
39
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
8
% V
% Trp:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
39
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _