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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHD8
All Species:
17.27
Human Site:
S2182
Identified Species:
31.67
UniProt:
Q9HCK8
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCK8
NP_065971.2
2581
290518
S2182
K
W
P
S
S
R
R
S
Q
E
M
V
T
G
G
Chimpanzee
Pan troglodytes
XP_001153522
2556
287735
S2157
K
W
P
S
S
R
R
S
Q
E
M
V
T
G
G
Rhesus Macaque
Macaca mulatta
XP_001096619
2585
291342
S2187
K
W
P
S
S
R
R
S
Q
E
M
V
T
G
G
Dog
Lupus familis
XP_532624
2304
262413
V1935
G
E
Y
G
D
S
P
V
P
T
P
R
S
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q09XV5
2582
290829
S2184
K
W
P
S
N
R
R
S
Q
E
V
T
A
G
G
Rat
Rattus norvegicus
Q9JIX5
2581
290674
S2182
K
W
P
S
N
R
R
S
Q
E
M
T
T
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512847
2876
321833
R2286
K
G
K
W
P
S
A
R
R
N
Y
D
S
N
T
Chicken
Gallus gallus
Q06A37
3011
338194
G2346
R
Q
M
F
D
F
Q
G
L
I
P
G
Y
T
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
B0R0I6
2511
279693
D2176
L
R
V
D
W
P
K
D
R
I
L
I
N
R
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KU24
1883
211809
R1570
E
T
E
K
K
E
W
R
S
N
L
W
Y
F
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22516
1787
205237
E1474
A
S
E
V
K
V
E
E
E
P
K
A
P
R
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S775
1384
158387
E1071
R
S
G
K
I
W
K
E
E
H
D
K
I
M
I
Baker's Yeast
Sacchar. cerevisiae
P32657
1468
168223
P1155
N
S
N
Y
K
D
D
P
L
K
F
S
L
G
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
97
87.8
N.A.
96.1
96.3
N.A.
48.5
43.4
N.A.
56.7
N.A.
23.9
N.A.
23
N.A.
Protein Similarity:
100
98.9
97.5
88.3
N.A.
97.8
97.8
N.A.
62
57
N.A.
68.6
N.A.
39.3
N.A.
37.6
N.A.
P-Site Identity:
100
100
100
0
N.A.
73.3
86.6
N.A.
6.6
0
N.A.
0
N.A.
0
N.A.
0
N.A.
P-Site Similarity:
100
100
100
6.6
N.A.
86.6
93.3
N.A.
20
13.3
N.A.
26.6
N.A.
13.3
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.9
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34.3
36
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
8
0
0
0
0
8
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
16
8
8
8
0
0
8
8
0
0
0
% D
% Glu:
8
8
16
0
0
8
8
16
16
39
0
0
0
0
0
% E
% Phe:
0
0
0
8
0
8
0
0
0
0
8
0
0
8
0
% F
% Gly:
8
8
8
8
0
0
0
8
0
0
0
8
0
47
39
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
16
0
8
8
0
16
% I
% Lys:
47
0
8
16
24
0
16
0
0
8
8
8
0
0
0
% K
% Leu:
8
0
0
0
0
0
0
0
16
0
16
0
8
0
8
% L
% Met:
0
0
8
0
0
0
0
0
0
0
31
0
0
8
0
% M
% Asn:
8
0
8
0
16
0
0
0
0
16
0
0
8
8
8
% N
% Pro:
0
0
39
0
8
8
8
8
8
8
16
0
8
0
8
% P
% Gln:
0
8
0
0
0
0
8
0
39
0
0
0
0
0
0
% Q
% Arg:
16
8
0
0
0
39
39
16
16
0
0
8
0
16
0
% R
% Ser:
0
24
0
39
24
16
0
39
8
0
0
8
16
8
8
% S
% Thr:
0
8
0
0
0
0
0
0
0
8
0
16
31
8
8
% T
% Val:
0
0
8
8
0
8
0
8
0
0
8
24
0
0
8
% V
% Trp:
0
39
0
8
8
8
8
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
8
8
0
0
0
0
0
0
8
0
16
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _