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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHD8
All Species:
18.79
Human Site:
S2223
Identified Species:
34.44
UniProt:
Q9HCK8
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCK8
NP_065971.2
2581
290518
S2223
P
R
S
S
S
A
A
S
M
A
E
E
E
A
S
Chimpanzee
Pan troglodytes
XP_001153522
2556
287735
S2198
P
R
S
S
S
A
A
S
M
A
E
E
E
A
S
Rhesus Macaque
Macaca mulatta
XP_001096619
2585
291342
S2228
P
R
S
S
S
A
A
S
M
A
E
E
E
A
S
Dog
Lupus familis
XP_532624
2304
262413
Q1976
D
E
K
E
F
T
V
Q
I
K
D
E
E
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q09XV5
2582
290829
S2225
P
R
S
G
S
A
A
S
M
A
E
E
E
A
S
Rat
Rattus norvegicus
Q9JIX5
2581
290674
S2223
P
R
S
S
S
A
A
S
M
V
E
E
E
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512847
2876
321833
E2327
P
P
S
T
G
V
R
E
E
H
D
Q
S
S
Q
Chicken
Gallus gallus
Q06A37
3011
338194
Q2387
E
D
I
T
A
S
P
Q
L
S
K
E
D
A
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
B0R0I6
2511
279693
G2217
V
S
D
E
H
E
L
G
D
D
L
G
Y
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KU24
1883
211809
K1611
G
E
A
K
G
K
D
K
G
S
S
G
S
P
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22516
1787
205237
W1515
N
G
K
E
Y
E
I
W
H
R
R
H
D
F
W
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S775
1384
158387
H1112
C
K
E
L
N
F
P
H
I
S
L
S
A
A
E
Baker's Yeast
Sacchar. cerevisiae
P32657
1468
168223
T1196
K
Y
G
Y
G
S
W
T
Q
I
R
D
D
P
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
97
87.8
N.A.
96.1
96.3
N.A.
48.5
43.4
N.A.
56.7
N.A.
23.9
N.A.
23
N.A.
Protein Similarity:
100
98.9
97.5
88.3
N.A.
97.8
97.8
N.A.
62
57
N.A.
68.6
N.A.
39.3
N.A.
37.6
N.A.
P-Site Identity:
100
100
100
13.3
N.A.
93.3
93.3
N.A.
13.3
13.3
N.A.
0
N.A.
0
N.A.
0
N.A.
P-Site Similarity:
100
100
100
26.6
N.A.
93.3
93.3
N.A.
40
60
N.A.
6.6
N.A.
20
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.9
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34.3
36
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
39
39
0
0
31
0
0
8
54
8
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
8
0
0
0
8
0
8
8
16
8
24
0
0
% D
% Glu:
8
16
8
24
0
16
0
8
8
0
39
54
47
0
8
% E
% Phe:
0
0
0
0
8
8
0
0
0
0
0
0
0
8
8
% F
% Gly:
8
8
8
8
24
0
0
8
8
0
0
16
0
8
0
% G
% His:
0
0
0
0
8
0
0
8
8
8
0
8
0
0
0
% H
% Ile:
0
0
8
0
0
0
8
0
16
8
0
0
0
0
0
% I
% Lys:
8
8
16
8
0
8
0
8
0
8
8
0
0
0
0
% K
% Leu:
0
0
0
8
0
0
8
0
8
0
16
0
0
0
16
% L
% Met:
0
0
0
0
0
0
0
0
39
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
47
8
0
0
0
0
16
0
0
0
0
0
0
16
0
% P
% Gln:
0
0
0
0
0
0
0
16
8
0
0
8
0
0
8
% Q
% Arg:
0
39
0
0
0
0
8
0
0
8
16
0
0
0
8
% R
% Ser:
0
8
47
31
39
16
0
39
0
24
8
8
16
16
39
% S
% Thr:
0
0
0
16
0
8
0
8
0
0
0
0
0
0
0
% T
% Val:
8
0
0
0
0
8
8
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
8
% W
% Tyr:
0
8
0
8
8
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _