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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHD8
All Species:
8.79
Human Site:
S522
Identified Species:
16.11
UniProt:
Q9HCK8
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCK8
NP_065971.2
2581
290518
S522
K
P
K
K
S
K
T
S
G
A
S
K
T
K
G
Chimpanzee
Pan troglodytes
XP_001153522
2556
287735
S497
K
P
K
K
S
K
T
S
G
A
S
K
T
K
G
Rhesus Macaque
Macaca mulatta
XP_001096619
2585
291342
S527
K
P
K
K
N
K
T
S
G
T
S
K
T
K
G
Dog
Lupus familis
XP_532624
2304
262413
K471
P
V
I
Y
Y
L
V
K
W
C
S
L
P
Y
E
Cat
Felis silvestris
Mouse
Mus musculus
Q09XV5
2582
290829
A524
K
P
K
K
S
K
T
A
A
A
S
K
T
K
G
Rat
Rattus norvegicus
Q9JIX5
2581
290674
A522
K
P
K
K
S
K
T
A
A
A
S
K
T
K
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512847
2876
321833
P544
E
R
G
E
R
N
I
P
R
V
M
S
P
E
N
Chicken
Gallus gallus
Q06A37
3011
338194
E669
K
E
P
K
E
K
K
E
P
K
T
P
K
V
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
B0R0I6
2511
279693
P553
K
A
K
T
P
V
I
P
G
G
G
S
K
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KU24
1883
211809
N123
N
Q
S
I
N
N
A
N
T
S
S
S
L
P
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22516
1787
205237
D27
M
L
A
E
G
H
E
D
G
E
E
D
V
G
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S775
1384
158387
Baker's Yeast
Sacchar. cerevisiae
P32657
1468
168223
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
97
87.8
N.A.
96.1
96.3
N.A.
48.5
43.4
N.A.
56.7
N.A.
23.9
N.A.
23
N.A.
Protein Similarity:
100
98.9
97.5
88.3
N.A.
97.8
97.8
N.A.
62
57
N.A.
68.6
N.A.
39.3
N.A.
37.6
N.A.
P-Site Identity:
100
100
86.6
6.6
N.A.
86.6
86.6
N.A.
0
20
N.A.
20
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
100
93.3
6.6
N.A.
93.3
93.3
N.A.
20
26.6
N.A.
20
N.A.
26.6
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.9
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34.3
36
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
0
8
16
16
31
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% D
% Glu:
8
8
0
16
8
0
8
8
0
8
8
0
0
8
16
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
8
0
0
0
39
8
8
0
0
8
39
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
8
0
0
16
0
0
0
0
0
0
0
0
% I
% Lys:
54
0
47
47
0
47
8
8
0
8
0
39
16
39
16
% K
% Leu:
0
8
0
0
0
8
0
0
0
0
0
8
8
0
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
8
0
0
0
16
16
0
8
0
0
0
0
0
0
8
% N
% Pro:
8
39
8
0
8
0
0
16
8
0
0
8
16
8
8
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
0
8
0
0
0
8
0
0
0
0
0
0
% R
% Ser:
0
0
8
0
31
0
0
24
0
8
54
24
0
8
0
% S
% Thr:
0
0
0
8
0
0
39
0
8
8
8
0
39
0
0
% T
% Val:
0
8
0
0
0
8
8
0
0
8
0
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
8
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _