KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHD8
All Species:
31.82
Human Site:
T1351
Identified Species:
58.33
UniProt:
Q9HCK8
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCK8
NP_065971.2
2581
290518
T1351
E
S
E
G
K
G
S
T
F
A
K
A
S
F
V
Chimpanzee
Pan troglodytes
XP_001153522
2556
287735
T1326
E
S
E
G
K
G
S
T
F
A
K
A
S
F
V
Rhesus Macaque
Macaca mulatta
XP_001096619
2585
291342
T1356
E
S
E
G
K
G
S
T
F
A
K
A
S
F
V
Dog
Lupus familis
XP_532624
2304
262413
K1236
I
S
P
A
E
N
G
K
T
K
E
L
Q
N
H
Cat
Felis silvestris
Mouse
Mus musculus
Q09XV5
2582
290829
T1353
E
S
E
G
K
G
S
T
F
A
K
A
S
F
V
Rat
Rattus norvegicus
Q9JIX5
2581
290674
T1351
E
S
E
G
K
G
S
T
F
A
K
A
S
F
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512847
2876
321833
T1400
E
S
E
G
R
G
S
T
F
A
K
A
S
F
V
Chicken
Gallus gallus
Q06A37
3011
338194
T1509
E
S
E
G
K
G
S
T
F
A
K
A
S
F
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
B0R0I6
2511
279693
T1386
E
S
E
G
K
G
S
T
F
S
K
A
S
F
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KU24
1883
211809
K874
V
L
A
D
Y
L
Q
K
R
H
F
P
F
Q
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22516
1787
205237
N778
N
Q
S
T
F
F
K
N
L
R
E
Y
N
I
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S775
1384
158387
I375
L
S
K
D
Q
K
K
I
K
K
K
K
S
G
Q
Baker's Yeast
Sacchar. cerevisiae
P32657
1468
168223
N459
N
C
I
C
Y
M
G
N
Q
K
S
R
D
T
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
97
87.8
N.A.
96.1
96.3
N.A.
48.5
43.4
N.A.
56.7
N.A.
23.9
N.A.
23
N.A.
Protein Similarity:
100
98.9
97.5
88.3
N.A.
97.8
97.8
N.A.
62
57
N.A.
68.6
N.A.
39.3
N.A.
37.6
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
100
100
N.A.
93.3
100
N.A.
93.3
N.A.
0
N.A.
0
N.A.
P-Site Similarity:
100
100
100
20
N.A.
100
100
N.A.
100
100
N.A.
100
N.A.
0
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.9
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34.3
36
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
0
0
0
0
0
54
0
62
0
0
0
% A
% Cys:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
16
0
0
0
0
0
0
0
0
8
0
0
% D
% Glu:
62
0
62
0
8
0
0
0
0
0
16
0
0
0
0
% E
% Phe:
0
0
0
0
8
8
0
0
62
0
8
0
8
62
0
% F
% Gly:
0
0
0
62
0
62
16
0
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% H
% Ile:
8
0
8
0
0
0
0
8
0
0
0
0
0
8
8
% I
% Lys:
0
0
8
0
54
8
16
16
8
24
70
8
0
0
0
% K
% Leu:
8
8
0
0
0
8
0
0
8
0
0
8
0
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
16
0
0
0
0
8
0
16
0
0
0
0
8
8
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% P
% Gln:
0
8
0
0
8
0
8
0
8
0
0
0
8
8
16
% Q
% Arg:
0
0
0
0
8
0
0
0
8
8
0
8
0
0
8
% R
% Ser:
0
77
8
0
0
0
62
0
0
8
8
0
70
0
0
% S
% Thr:
0
0
0
8
0
0
0
62
8
0
0
0
0
8
0
% T
% Val:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
62
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
16
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _