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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHD8
All Species:
29.09
Human Site:
T1812
Identified Species:
53.33
UniProt:
Q9HCK8
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCK8
NP_065971.2
2581
290518
T1812
D
F
Y
R
V
V
S
T
F
G
V
E
Y
D
P
Chimpanzee
Pan troglodytes
XP_001153522
2556
287735
T1787
D
F
Y
R
V
V
S
T
F
G
V
E
Y
D
P
Rhesus Macaque
Macaca mulatta
XP_001096619
2585
291342
T1817
D
F
Y
R
V
V
S
T
F
G
V
E
Y
D
P
Dog
Lupus familis
XP_532624
2304
262413
L1627
Q
V
L
C
H
P
L
L
E
D
R
L
A
L
C
Cat
Felis silvestris
Mouse
Mus musculus
Q09XV5
2582
290829
T1814
D
F
Y
R
V
V
S
T
F
G
V
E
Y
D
P
Rat
Rattus norvegicus
Q9JIX5
2581
290674
T1812
D
F
Y
R
V
V
S
T
F
G
V
E
Y
D
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512847
2876
321833
T1852
D
F
Y
R
V
V
S
T
F
G
V
V
F
D
P
Chicken
Gallus gallus
Q06A37
3011
338194
T1980
D
F
Y
R
V
V
S
T
F
G
I
I
F
D
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
B0R0I6
2511
279693
K1866
F
G
V
E
R
I
K
K
E
T
D
A
P
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KU24
1883
211809
Q1264
D
E
T
P
G
A
K
Q
R
R
A
R
A
T
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22516
1787
205237
K1168
E
G
Q
D
G
E
K
K
E
H
W
T
N
E
Y
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S775
1384
158387
S765
D
D
I
I
R
Y
G
S
K
E
L
F
A
S
E
Baker's Yeast
Sacchar. cerevisiae
P32657
1468
168223
T849
A
I
I
S
L
G
V
T
D
G
N
K
Y
T
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
97
87.8
N.A.
96.1
96.3
N.A.
48.5
43.4
N.A.
56.7
N.A.
23.9
N.A.
23
N.A.
Protein Similarity:
100
98.9
97.5
88.3
N.A.
97.8
97.8
N.A.
62
57
N.A.
68.6
N.A.
39.3
N.A.
37.6
N.A.
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
86.6
80
N.A.
0
N.A.
6.6
N.A.
0
N.A.
P-Site Similarity:
100
100
100
0
N.A.
100
100
N.A.
93.3
93.3
N.A.
13.3
N.A.
6.6
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.9
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34.3
36
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
8
0
0
0
0
8
8
24
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
70
8
0
8
0
0
0
0
8
8
8
0
0
54
0
% D
% Glu:
8
8
0
8
0
8
0
0
24
8
0
39
0
16
8
% E
% Phe:
8
54
0
0
0
0
0
0
54
0
0
8
16
0
8
% F
% Gly:
0
16
0
0
16
8
8
0
0
62
0
0
0
0
8
% G
% His:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
8
16
8
0
8
0
0
0
0
8
8
0
0
0
% I
% Lys:
0
0
0
0
0
0
24
16
8
0
0
8
0
0
8
% K
% Leu:
0
0
8
0
8
0
8
8
0
0
8
8
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
0
% N
% Pro:
0
0
0
8
0
8
0
0
0
0
0
0
8
0
54
% P
% Gln:
8
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
54
16
0
0
0
8
8
8
8
0
0
0
% R
% Ser:
0
0
0
8
0
0
54
8
0
0
0
0
0
8
0
% S
% Thr:
0
0
8
0
0
0
0
62
0
8
0
8
0
16
0
% T
% Val:
0
8
8
0
54
54
8
0
0
0
47
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
54
0
0
8
0
0
0
0
0
0
47
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _