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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHD8
All Species:
16.06
Human Site:
T2050
Identified Species:
29.44
UniProt:
Q9HCK8
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCK8
NP_065971.2
2581
290518
T2050
M
R
V
S
P
S
D
T
T
P
L
V
S
R
S
Chimpanzee
Pan troglodytes
XP_001153522
2556
287735
T2025
M
R
V
S
P
S
D
T
T
P
L
V
S
R
S
Rhesus Macaque
Macaca mulatta
XP_001096619
2585
291342
T2055
M
R
V
A
P
S
D
T
T
P
L
V
S
R
S
Dog
Lupus familis
XP_532624
2304
262413
S1808
P
S
S
S
S
S
S
S
S
S
S
S
S
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q09XV5
2582
290829
T2052
V
R
V
G
S
S
D
T
A
P
L
S
R
S
V
Rat
Rattus norvegicus
Q9JIX5
2581
290674
T2050
I
R
V
A
S
S
D
T
A
P
L
S
R
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512847
2876
321833
Q2087
P
K
N
G
V
W
S
Q
T
P
A
D
Q
K
S
Chicken
Gallus gallus
Q06A37
3011
338194
K2217
E
A
E
T
G
S
V
K
C
E
L
K
D
I
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
B0R0I6
2511
279693
E2047
G
I
K
E
E
G
L
E
D
E
S
R
L
L
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KU24
1883
211809
V1444
A
E
S
S
N
S
Q
V
D
P
S
T
A
S
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22516
1787
205237
N1348
W
Q
V
R
D
L
R
N
K
S
E
K
V
F
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S775
1384
158387
G945
T
P
L
M
E
G
E
G
R
S
F
R
V
L
G
Baker's Yeast
Sacchar. cerevisiae
P32657
1468
168223
K1029
I
L
K
F
G
N
L
K
E
I
L
D
E
L
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
97
87.8
N.A.
96.1
96.3
N.A.
48.5
43.4
N.A.
56.7
N.A.
23.9
N.A.
23
N.A.
Protein Similarity:
100
98.9
97.5
88.3
N.A.
97.8
97.8
N.A.
62
57
N.A.
68.6
N.A.
39.3
N.A.
37.6
N.A.
P-Site Identity:
100
100
93.3
26.6
N.A.
46.6
46.6
N.A.
20
13.3
N.A.
0
N.A.
20
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
40
N.A.
53.3
60
N.A.
33.3
20
N.A.
0
N.A.
26.6
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.9
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34.3
36
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
16
0
0
0
0
16
0
8
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
39
0
16
0
0
16
8
0
0
% D
% Glu:
8
8
8
8
16
0
8
8
8
16
8
0
8
0
8
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
8
0
0
8
0
% F
% Gly:
8
0
0
16
16
16
0
8
0
0
0
0
0
0
16
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
16
8
0
0
0
0
0
0
0
8
0
0
0
8
8
% I
% Lys:
0
8
16
0
0
0
0
16
8
0
0
16
0
8
8
% K
% Leu:
0
8
8
0
0
8
16
0
0
0
54
0
8
24
0
% L
% Met:
24
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
8
8
0
8
0
0
0
0
0
0
0
% N
% Pro:
16
8
0
0
24
0
0
0
0
54
0
0
0
0
8
% P
% Gln:
0
8
0
0
0
0
8
8
0
0
0
0
8
0
0
% Q
% Arg:
0
39
0
8
0
0
8
0
8
0
0
16
16
24
0
% R
% Ser:
0
8
16
31
24
62
16
8
8
24
24
24
31
31
39
% S
% Thr:
8
0
0
8
0
0
0
39
31
0
0
8
0
0
0
% T
% Val:
8
0
47
0
8
0
8
8
0
0
0
24
16
0
16
% V
% Trp:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _