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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHD8
All Species:
20
Human Site:
Y1566
Identified Species:
36.67
UniProt:
Q9HCK8
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCK8
NP_065971.2
2581
290518
Y1566
T
L
F
Q
D
E
S
Y
K
K
H
L
K
H
Q
Chimpanzee
Pan troglodytes
XP_001153522
2556
287735
Y1541
T
L
F
Q
D
E
S
Y
K
K
H
L
K
H
Q
Rhesus Macaque
Macaca mulatta
XP_001096619
2585
291342
Y1571
T
L
F
Q
D
E
S
Y
K
K
H
L
K
H
Q
Dog
Lupus familis
XP_532624
2304
262413
V1443
M
M
D
E
E
I
S
V
I
D
G
D
E
A
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q09XV5
2582
290829
Y1568
T
L
F
Q
D
E
S
Y
K
K
H
L
K
H
Q
Rat
Rattus norvegicus
Q9JIX5
2581
290674
Y1566
T
L
F
Q
D
E
S
Y
K
K
H
L
K
H
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512847
2876
321833
G1615
E
H
L
L
Q
D
E
G
Y
K
K
H
I
K
H
Chicken
Gallus gallus
Q06A37
3011
338194
S1727
D
V
L
F
Q
E
D
S
Y
R
K
H
L
K
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
B0R0I6
2511
279693
S1609
D
S
L
L
L
D
D
S
Y
R
K
H
L
K
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KU24
1883
211809
S1081
F
E
E
E
P
S
D
S
V
S
K
Q
D
Q
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22516
1787
205237
R985
V
E
G
Y
K
Y
E
R
I
D
G
S
I
T
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S775
1384
158387
D582
G
V
E
P
V
I
H
D
A
N
E
A
F
K
Q
Baker's Yeast
Sacchar. cerevisiae
P32657
1468
168223
D666
S
N
H
P
Y
L
F
D
N
A
E
E
R
V
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
97
87.8
N.A.
96.1
96.3
N.A.
48.5
43.4
N.A.
56.7
N.A.
23.9
N.A.
23
N.A.
Protein Similarity:
100
98.9
97.5
88.3
N.A.
97.8
97.8
N.A.
62
57
N.A.
68.6
N.A.
39.3
N.A.
37.6
N.A.
P-Site Identity:
100
100
100
13.3
N.A.
100
100
N.A.
6.6
6.6
N.A.
0
N.A.
0
N.A.
0
N.A.
P-Site Similarity:
100
100
100
40
N.A.
100
100
N.A.
13.3
20
N.A.
13.3
N.A.
6.6
N.A.
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.9
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34.3
36
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
8
8
0
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
0
8
0
39
16
24
16
0
16
0
8
8
0
0
% D
% Glu:
8
16
16
16
8
47
16
0
0
0
16
8
8
0
0
% E
% Phe:
8
0
39
8
0
0
8
0
0
0
0
0
8
0
0
% F
% Gly:
8
0
8
0
0
0
0
8
0
0
16
0
0
0
8
% G
% His:
0
8
8
0
0
0
8
0
0
0
39
24
0
39
24
% H
% Ile:
0
0
0
0
0
16
0
0
16
0
0
0
16
0
0
% I
% Lys:
0
0
0
0
8
0
0
0
39
47
31
0
39
31
0
% K
% Leu:
0
39
24
16
8
8
0
0
0
0
0
39
16
0
8
% L
% Met:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
8
8
0
0
0
0
8
% N
% Pro:
0
0
0
16
8
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
39
16
0
0
0
0
0
0
8
0
8
54
% Q
% Arg:
0
0
0
0
0
0
0
8
0
16
0
0
8
0
0
% R
% Ser:
8
8
0
0
0
8
47
24
0
8
0
8
0
0
0
% S
% Thr:
39
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% T
% Val:
8
16
0
0
8
0
0
8
8
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
8
8
0
39
24
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _