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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHD8
All Species:
32.42
Human Site:
Y1642
Identified Species:
59.44
UniProt:
Q9HCK8
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCK8
NP_065971.2
2581
290518
Y1642
I
G
V
F
K
H
G
Y
E
K
Y
N
T
M
R
Chimpanzee
Pan troglodytes
XP_001153522
2556
287735
Y1617
I
G
V
F
K
H
G
Y
E
K
Y
N
T
M
R
Rhesus Macaque
Macaca mulatta
XP_001096619
2585
291342
Y1647
I
G
V
F
K
H
G
Y
E
K
Y
N
T
M
R
Dog
Lupus familis
XP_532624
2304
262413
I1510
A
A
F
K
L
K
E
I
A
R
R
E
K
Q
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q09XV5
2582
290829
Y1644
I
G
V
F
K
H
G
Y
E
K
Y
N
T
M
R
Rat
Rattus norvegicus
Q9JIX5
2581
290674
Y1642
I
G
V
F
K
H
G
Y
E
K
Y
N
T
M
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512847
2876
321833
Y1692
I
G
V
F
K
H
G
Y
E
K
Y
N
T
I
R
Chicken
Gallus gallus
Q06A37
3011
338194
Y1804
I
G
V
F
K
H
G
Y
E
K
Y
N
S
M
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
B0R0I6
2511
279693
Y1686
I
G
V
Y
K
H
G
Y
E
M
Y
T
T
M
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KU24
1883
211809
K1147
R
G
A
G
K
G
G
K
G
K
Q
Q
A
D
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22516
1787
205237
H1051
I
Q
A
F
S
R
A
H
R
L
G
Q
K
H
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S775
1384
158387
A648
I
D
G
K
V
G
G
A
E
R
Q
I
R
I
D
Baker's Yeast
Sacchar. cerevisiae
P32657
1468
168223
S732
D
I
L
G
D
Y
L
S
I
K
G
I
N
F
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
97
87.8
N.A.
96.1
96.3
N.A.
48.5
43.4
N.A.
56.7
N.A.
23.9
N.A.
23
N.A.
Protein Similarity:
100
98.9
97.5
88.3
N.A.
97.8
97.8
N.A.
62
57
N.A.
68.6
N.A.
39.3
N.A.
37.6
N.A.
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
93.3
93.3
N.A.
80
N.A.
26.6
N.A.
13.3
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
100
100
N.A.
86.6
N.A.
26.6
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.9
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34.3
36
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
16
0
0
0
8
8
8
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
0
8
0
0
0
0
0
0
0
0
8
16
% D
% Glu:
0
0
0
0
0
0
8
0
70
0
0
8
0
0
0
% E
% Phe:
0
0
8
62
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
70
8
16
0
16
77
0
8
0
16
0
0
0
0
% G
% His:
0
0
0
0
0
62
0
8
0
0
0
0
0
8
0
% H
% Ile:
77
8
0
0
0
0
0
8
8
0
0
16
0
16
0
% I
% Lys:
0
0
0
16
70
8
0
8
0
70
0
0
16
0
8
% K
% Leu:
0
0
8
0
8
0
8
0
0
8
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
54
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
54
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
16
16
0
8
16
% Q
% Arg:
8
0
0
0
0
8
0
0
8
16
8
0
8
0
62
% R
% Ser:
0
0
0
0
8
0
0
8
0
0
0
0
8
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
8
54
0
0
% T
% Val:
0
0
62
0
8
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
8
0
62
0
0
62
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _