KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPAM
All Species:
27.88
Human Site:
S412
Identified Species:
51.11
UniProt:
Q9HCL2
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCL2
NP_065969.3
828
93795
S412
S
L
K
E
Y
L
E
S
Q
S
Q
K
P
V
S
Chimpanzee
Pan troglodytes
XP_001145374
828
93723
S412
S
L
K
E
Y
L
E
S
Q
S
Q
K
P
V
S
Rhesus Macaque
Macaca mulatta
XP_001088103
828
93815
S412
S
L
K
E
Y
L
E
S
Q
S
Q
K
P
V
S
Dog
Lupus familis
XP_544020
828
93648
S412
S
L
K
E
Y
L
E
S
Q
S
Q
K
P
V
S
Cat
Felis silvestris
Mouse
Mus musculus
Q61586
827
93671
G412
S
L
K
E
Y
L
E
G
Q
S
Q
K
P
V
S
Rat
Rattus norvegicus
P97564
828
93696
G412
S
L
K
E
Y
L
E
G
Q
S
Q
K
P
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513362
829
94118
S413
S
L
K
E
Y
L
E
S
Q
S
Q
K
P
M
L
Chicken
Gallus gallus
XP_421757
828
94191
S412
S
L
K
E
Y
V
N
S
Q
S
Q
K
T
V
P
Frog
Xenopus laevis
NP_001091387
822
93021
T411
S
L
K
E
Y
L
E
T
Q
T
Q
K
P
P
P
Zebra Danio
Brachydanio rerio
XP_683857
369
41594
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_733237
786
88294
A385
V
N
S
Y
N
K
I
A
R
E
D
G
N
I
A
Honey Bee
Apis mellifera
XP_395192
864
99523
S442
S
L
R
E
M
L
T
S
L
Q
N
Q
P
Q
L
Nematode Worm
Caenorhab. elegans
Q22949
718
82053
G317
K
V
R
E
S
V
L
G
V
F
R
G
I
F
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.6
95.7
N.A.
92.5
91.6
N.A.
86.9
81.4
69.8
31.8
N.A.
26
29.2
26.4
N.A.
Protein Similarity:
100
99.8
99.6
97.7
N.A.
96.3
95.7
N.A.
92.6
89.3
83.2
37.2
N.A.
48.4
49.6
47.4
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
86.6
73.3
73.3
0
N.A.
0
40
13.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
93.3
80
86.6
0
N.A.
26.6
53.3
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% D
% Glu:
0
0
0
85
0
0
62
0
0
8
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% F
% Gly:
0
0
0
0
0
0
0
24
0
0
0
16
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
0
0
8
8
0
% I
% Lys:
8
0
70
0
0
8
0
0
0
0
0
70
0
0
0
% K
% Leu:
0
77
0
0
0
70
8
0
8
0
0
0
0
0
16
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
8
0
0
8
0
8
0
0
0
8
0
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
70
8
16
% P
% Gln:
0
0
0
0
0
0
0
0
70
8
70
8
0
8
0
% Q
% Arg:
0
0
16
0
0
0
0
0
8
0
8
0
0
0
0
% R
% Ser:
77
0
8
0
8
0
0
54
0
62
0
0
0
0
54
% S
% Thr:
0
0
0
0
0
0
8
8
0
8
0
0
8
0
0
% T
% Val:
8
8
0
0
0
16
0
0
8
0
0
0
0
54
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
70
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _