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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GPAM All Species: 25.15
Human Site: S611 Identified Species: 46.11
UniProt: Q9HCL2 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HCL2 NP_065969.3 828 93795 S611 S T P P N L I S Q E Q L V R K
Chimpanzee Pan troglodytes XP_001145374 828 93723 S611 S T P P N L I S Q E Q L V R K
Rhesus Macaque Macaca mulatta XP_001088103 828 93815 S611 G T P P N L I S Q E Q L V R K
Dog Lupus familis XP_544020 828 93648 S611 G T S P S L V S Q E Q L V R K
Cat Felis silvestris
Mouse Mus musculus Q61586 827 93671 I610 A G G L G N L I S Q E Q L V R
Rat Rattus norvegicus P97564 828 93696 S611 G G L G N L I S Q E Q L V R K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513362 829 94118 S612 G I S S N L I S Q E Q L V R K
Chicken Gallus gallus XP_421757 828 94191 S611 G A S P S L I S Q E H L V R K
Frog Xenopus laevis NP_001091387 822 93021 I607 N G S S D G A I S Q E F L I R
Zebra Danio Brachydanio rerio XP_683857 369 41594 V157 Q E D A E P G V D P K A V S K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_733237 786 88294 L574 K K L I D T A L E N C Q I Y R
Honey Bee Apis mellifera XP_395192 864 99523 S643 T Q N N I T V S Q D V L I E K
Nematode Worm Caenorhab. elegans Q22949 718 82053 I506 A Y N K N S V I C R F S I K S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 98.6 95.7 N.A. 92.5 91.6 N.A. 86.9 81.4 69.8 31.8 N.A. 26 29.2 26.4 N.A.
Protein Similarity: 100 99.8 99.6 97.7 N.A. 96.3 95.7 N.A. 92.6 89.3 83.2 37.2 N.A. 48.4 49.6 47.4 N.A.
P-Site Identity: 100 100 93.3 73.3 N.A. 0 73.3 N.A. 73.3 66.6 0 13.3 N.A. 0 26.6 6.6 N.A.
P-Site Similarity: 100 100 93.3 86.6 N.A. 40 73.3 N.A. 73.3 73.3 40 20 N.A. 26.6 53.3 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 8 0 8 0 0 16 0 0 0 0 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 8 0 0 0 0 % C
% Asp: 0 0 8 0 16 0 0 0 8 8 0 0 0 0 0 % D
% Glu: 0 8 0 0 8 0 0 0 8 54 16 0 0 8 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 8 8 0 0 0 % F
% Gly: 39 24 8 8 8 8 8 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % H
% Ile: 0 8 0 8 8 0 47 24 0 0 0 0 24 8 0 % I
% Lys: 8 8 0 8 0 0 0 0 0 0 8 0 0 8 70 % K
% Leu: 0 0 16 8 0 54 8 8 0 0 0 62 16 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 16 8 47 8 0 0 0 8 0 0 0 0 0 % N
% Pro: 0 0 24 39 0 8 0 0 0 8 0 0 0 0 0 % P
% Gln: 8 8 0 0 0 0 0 0 62 16 47 16 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 8 0 0 0 54 24 % R
% Ser: 16 0 31 16 16 8 0 62 16 0 0 8 0 8 8 % S
% Thr: 8 31 0 0 0 16 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 24 8 0 0 8 0 62 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 0 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _