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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPAM
All Species:
36.67
Human Site:
Y705
Identified Species:
67.22
UniProt:
Q9HCL2
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCL2
NP_065969.3
828
93795
Y705
G
E
E
Q
R
D
C
Y
L
K
V
S
Q
S
K
Chimpanzee
Pan troglodytes
XP_001145374
828
93723
Y705
G
E
E
Q
R
D
C
Y
L
K
V
S
Q
S
K
Rhesus Macaque
Macaca mulatta
XP_001088103
828
93815
Y705
G
E
E
Q
R
D
C
Y
L
K
V
S
Q
S
K
Dog
Lupus familis
XP_544020
828
93648
Y705
G
E
E
Q
R
D
C
Y
L
K
V
S
Q
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q61586
827
93671
Y704
G
E
E
Q
R
D
C
Y
L
K
V
S
Q
S
K
Rat
Rattus norvegicus
P97564
828
93696
Y705
G
E
E
Q
R
D
C
Y
L
K
V
S
Q
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513362
829
94118
Y706
G
E
E
Q
R
D
C
Y
L
K
V
S
Q
S
K
Chicken
Gallus gallus
XP_421757
828
94191
Y705
G
E
E
Q
R
D
C
Y
L
K
V
S
Q
S
Q
Frog
Xenopus laevis
NP_001091387
822
93021
Y701
G
E
E
Q
R
D
R
Y
L
K
M
S
P
C
E
Zebra Danio
Brachydanio rerio
XP_683857
369
41594
P251
F
C
H
N
I
K
A
P
H
I
A
A
G
N
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_733237
786
88294
C668
P
S
Q
Q
R
Y
I
C
E
V
L
A
P
F
A
Honey Bee
Apis mellifera
XP_395192
864
99523
Y737
L
Q
P
L
I
D
T
Y
T
F
S
A
F
I
L
Nematode Worm
Caenorhab. elegans
Q22949
718
82053
R600
A
L
N
S
G
T
L
R
V
R
D
A
K
S
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.6
95.7
N.A.
92.5
91.6
N.A.
86.9
81.4
69.8
31.8
N.A.
26
29.2
26.4
N.A.
Protein Similarity:
100
99.8
99.6
97.7
N.A.
96.3
95.7
N.A.
92.6
89.3
83.2
37.2
N.A.
48.4
49.6
47.4
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
93.3
N.A.
100
93.3
66.6
0
N.A.
13.3
13.3
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
80
13.3
N.A.
33.3
26.6
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
8
0
0
0
8
31
0
8
8
% A
% Cys:
0
8
0
0
0
0
62
8
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
0
0
77
0
0
0
0
8
0
0
0
0
% D
% Glu:
0
70
70
0
0
0
0
0
8
0
0
0
0
0
8
% E
% Phe:
8
0
0
0
0
0
0
0
0
8
0
0
8
8
0
% F
% Gly:
70
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% G
% His:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
16
0
8
0
0
8
0
0
0
8
0
% I
% Lys:
0
0
0
0
0
8
0
0
0
70
0
0
8
0
54
% K
% Leu:
8
8
0
8
0
0
8
0
70
0
8
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
8
8
0
0
0
0
0
0
0
0
0
8
8
% N
% Pro:
8
0
8
0
0
0
0
8
0
0
0
0
16
0
0
% P
% Gln:
0
8
8
77
0
0
0
0
0
0
0
0
62
0
8
% Q
% Arg:
0
0
0
0
77
0
8
8
0
8
0
0
0
0
8
% R
% Ser:
0
8
0
8
0
0
0
0
0
0
8
70
0
62
0
% S
% Thr:
0
0
0
0
0
8
8
0
8
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
8
8
62
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
77
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _