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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPB41L5
All Species:
11.52
Human Site:
S521
Identified Species:
19.49
UniProt:
Q9HCM4
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCM4
NP_065960.2
733
81856
S521
M
E
N
S
P
L
L
S
P
R
S
N
I
D
V
Chimpanzee
Pan troglodytes
XP_001157953
733
81845
S521
M
E
N
S
P
L
L
S
P
R
S
N
I
D
V
Rhesus Macaque
Macaca mulatta
XP_001088764
726
81122
E515
L
F
K
G
I
I
T
E
N
S
P
N
L
E
K
Dog
Lupus familis
XP_532028
914
101864
G609
L
E
T
V
K
A
A
G
P
W
P
A
L
H
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGS1
731
81617
S520
T
E
Q
T
I
L
P
S
L
R
P
T
I
D
I
Rat
Rattus norvegicus
Q5FVG2
731
81700
S520
T
E
Q
N
I
L
P
S
L
R
P
A
I
D
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509941
820
90648
D521
P
K
N
S
N
V
Q
D
A
S
N
R
F
P
S
Chicken
Gallus gallus
XP_422083
502
57358
K293
V
E
D
D
E
Q
G
K
E
Q
E
H
T
F
V
Frog
Xenopus laevis
NP_001080234
498
57093
D289
T
L
V
V
V
E
D
D
E
Q
G
K
E
Q
E
Zebra Danio
Brachydanio rerio
O57457
619
70690
E410
E
K
P
S
A
P
W
E
E
D
A
P
Q
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650291
972
105216
P698
L
T
N
Q
M
F
V
P
A
A
H
S
S
N
M
Honey Bee
Apis mellifera
XP_623974
809
90976
S600
G
K
N
S
N
L
V
S
I
T
S
M
D
T
P
Nematode Worm
Caenorhab. elegans
P28191
1026
115075
P722
E
P
D
S
T
M
V
P
E
P
A
R
V
A
D
Sea Urchin
Strong. purpuratus
XP_788387
843
92835
H523
G
L
E
T
D
I
C
H
I
Q
P
N
T
A
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
95.2
39.8
N.A.
83.9
83.6
N.A.
56.5
56.6
54.4
28.5
N.A.
36.8
38.9
24.3
39.1
Protein Similarity:
100
99.3
96.3
52.1
N.A.
89.2
88.4
N.A.
65.1
62.2
60.9
44.7
N.A.
51.8
53.1
40.1
56.7
P-Site Identity:
100
100
6.6
13.3
N.A.
40
40
N.A.
13.3
13.3
0
6.6
N.A.
6.6
33.3
6.6
6.6
P-Site Similarity:
100
100
33.3
33.3
N.A.
53.3
53.3
N.A.
33.3
40
6.6
20
N.A.
40
46.6
40
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
8
8
0
15
8
15
15
0
15
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
15
8
8
0
8
15
0
8
0
0
8
29
8
% D
% Glu:
15
43
8
0
8
8
0
15
29
0
8
0
8
8
8
% E
% Phe:
0
8
0
0
0
8
0
0
0
0
0
0
8
8
0
% F
% Gly:
15
0
0
8
0
0
8
8
0
0
8
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
8
0
0
8
8
0
8
0
% H
% Ile:
0
0
0
0
22
15
0
0
15
0
0
0
29
0
22
% I
% Lys:
0
22
8
0
8
0
0
8
0
0
0
8
0
0
8
% K
% Leu:
22
15
0
0
0
36
15
0
15
0
0
0
15
0
0
% L
% Met:
15
0
0
0
8
8
0
0
0
0
0
8
0
0
8
% M
% Asn:
0
0
36
8
15
0
0
0
8
0
8
29
0
8
0
% N
% Pro:
8
8
8
0
15
8
15
15
22
8
36
8
0
8
8
% P
% Gln:
0
0
15
8
0
8
8
0
0
22
0
0
8
8
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
29
0
15
0
0
0
% R
% Ser:
0
0
0
43
0
0
0
36
0
15
22
8
8
8
15
% S
% Thr:
22
8
8
15
8
0
8
0
0
8
0
8
15
8
0
% T
% Val:
8
0
8
15
8
8
22
0
0
0
0
0
8
0
22
% V
% Trp:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _