KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPB41L5
All Species:
8.18
Human Site:
S670
Identified Species:
13.85
UniProt:
Q9HCM4
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCM4
NP_065960.2
733
81856
S670
P
R
W
I
V
P
Q
S
G
A
M
S
N
G
L
Chimpanzee
Pan troglodytes
XP_001157953
733
81845
S670
P
R
W
I
V
P
Q
S
G
V
M
S
N
G
L
Rhesus Macaque
Macaca mulatta
XP_001088764
726
81122
G664
P
R
W
I
V
P
S
G
A
M
S
N
G
L
A
Dog
Lupus familis
XP_532028
914
101864
H758
P
L
V
S
P
K
G
H
K
L
S
S
P
Q
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGS1
731
81617
A669
R
W
I
I
P
Q
S
A
T
I
S
N
G
L
A
Rat
Rattus norvegicus
Q5FVG2
731
81700
S669
R
W
I
I
P
Q
N
S
T
I
S
N
G
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509941
820
90648
S670
T
P
R
W
I
V
P
S
G
G
I
A
N
G
L
Chicken
Gallus gallus
XP_422083
502
57358
Q442
P
R
S
P
G
A
S
Q
H
D
K
W
P
F
D
Frog
Xenopus laevis
NP_001080234
498
57093
D438
S
P
G
A
G
Q
G
D
R
W
P
S
E
A
S
Zebra Danio
Brachydanio rerio
O57457
619
70690
S559
L
V
D
P
S
G
L
S
E
E
Q
L
K
E
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650291
972
105216
I847
I
L
I
N
E
I
F
I
N
N
I
I
N
N
N
Honey Bee
Apis mellifera
XP_623974
809
90976
A749
A
E
I
E
K
N
G
A
R
V
V
K
T
E
E
Nematode Worm
Caenorhab. elegans
P28191
1026
115075
F871
H
Q
Y
W
P
R
V
F
E
T
Q
E
Y
G
R
Sea Urchin
Strong. purpuratus
XP_788387
843
92835
L672
P
T
T
P
T
S
D
L
P
S
P
T
S
P
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
95.2
39.8
N.A.
83.9
83.6
N.A.
56.5
56.6
54.4
28.5
N.A.
36.8
38.9
24.3
39.1
Protein Similarity:
100
99.3
96.3
52.1
N.A.
89.2
88.4
N.A.
65.1
62.2
60.9
44.7
N.A.
51.8
53.1
40.1
56.7
P-Site Identity:
100
93.3
40
13.3
N.A.
6.6
13.3
N.A.
33.3
13.3
6.6
6.6
N.A.
6.6
0
6.6
6.6
P-Site Similarity:
100
93.3
46.6
13.3
N.A.
20
20
N.A.
53.3
13.3
6.6
13.3
N.A.
13.3
13.3
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
8
0
15
8
8
0
8
0
8
22
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
8
8
0
8
0
0
0
0
8
% D
% Glu:
0
8
0
8
8
0
0
0
15
8
0
8
8
15
8
% E
% Phe:
0
0
0
0
0
0
8
8
0
0
0
0
0
8
0
% F
% Gly:
0
0
8
0
15
8
22
8
22
8
0
0
22
29
0
% G
% His:
8
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% H
% Ile:
8
0
29
36
8
8
0
8
0
15
15
8
0
0
8
% I
% Lys:
0
0
0
0
8
8
0
0
8
0
8
8
8
0
8
% K
% Leu:
8
15
0
0
0
0
8
8
0
8
0
8
0
22
22
% L
% Met:
0
0
0
0
0
0
0
0
0
8
15
0
0
0
0
% M
% Asn:
0
0
0
8
0
8
8
0
8
8
0
22
29
8
15
% N
% Pro:
43
15
0
22
29
22
8
0
8
0
15
0
15
8
0
% P
% Gln:
0
8
0
0
0
22
15
8
0
0
15
0
0
8
0
% Q
% Arg:
15
29
8
0
0
8
0
0
15
0
0
0
0
0
8
% R
% Ser:
8
0
8
8
8
8
22
36
0
8
29
29
8
0
8
% S
% Thr:
8
8
8
0
8
0
0
0
15
8
0
8
8
0
0
% T
% Val:
0
8
8
0
22
8
8
0
0
15
8
0
0
0
0
% V
% Trp:
0
15
22
15
0
0
0
0
0
8
0
8
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _