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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM8A
All Species:
11.52
Human Site:
S375
Identified Species:
28.15
UniProt:
Q9HCN3
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCN3
NP_067082.2
771
84761
S375
F
Q
P
L
D
R
V
S
V
R
V
C
S
D
T
Chimpanzee
Pan troglodytes
XP_510709
772
85322
S376
F
Q
P
L
D
R
V
S
V
R
V
C
S
D
T
Rhesus Macaque
Macaca mulatta
XP_001118461
757
84009
S361
F
Q
L
L
D
R
V
S
V
R
V
C
P
N
T
Dog
Lupus familis
XP_537022
836
91805
S440
F
W
P
A
D
R
V
S
V
L
V
R
S
G
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9ESN3
769
85310
F373
F
Q
P
L
N
G
A
F
V
L
V
H
S
S
M
Rat
Rattus norvegicus
NP_001100461
772
85580
N373
S
V
H
F
Q
P
L
N
G
A
F
V
L
V
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512398
383
42381
Chicken
Gallus gallus
XP_425255
614
68106
L237
G
G
S
L
V
V
N
L
L
L
N
K
T
S
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651350
993
111910
E557
R
L
I
G
D
P
K
E
E
V
V
P
A
V
S
Honey Bee
Apis mellifera
XP_396233
738
84407
A358
G
G
T
L
D
I
S
A
H
L
E
M
D
K
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.4
90.2
66.2
N.A.
75.7
76
N.A.
28.2
47.5
N.A.
N.A.
N.A.
22.7
25.1
N.A.
N.A.
Protein Similarity:
100
95.3
93
74
N.A.
83.7
83.5
N.A.
36.9
59.2
N.A.
N.A.
N.A.
40.2
43.8
N.A.
N.A.
P-Site Identity:
100
100
80
66.6
N.A.
46.6
0
N.A.
0
6.6
N.A.
N.A.
N.A.
13.3
13.3
N.A.
N.A.
P-Site Similarity:
100
100
86.6
66.6
N.A.
53.3
13.3
N.A.
0
20
N.A.
N.A.
N.A.
26.6
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
10
10
0
10
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
30
0
0
0
% C
% Asp:
0
0
0
0
60
0
0
0
0
0
0
0
10
20
0
% D
% Glu:
0
0
0
0
0
0
0
10
10
0
10
0
0
0
0
% E
% Phe:
50
0
0
10
0
0
0
10
0
0
10
0
0
0
0
% F
% Gly:
20
20
0
10
0
10
0
0
10
0
0
0
0
10
0
% G
% His:
0
0
10
0
0
0
0
0
10
0
0
10
0
0
10
% H
% Ile:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
10
0
0
0
0
10
0
10
0
% K
% Leu:
0
10
10
60
0
0
10
10
10
40
0
0
10
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% M
% Asn:
0
0
0
0
10
0
10
10
0
0
10
0
0
10
0
% N
% Pro:
0
0
40
0
0
20
0
0
0
0
0
10
10
0
0
% P
% Gln:
0
40
0
0
10
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
0
0
0
0
40
0
0
0
30
0
10
0
0
0
% R
% Ser:
10
0
10
0
0
0
10
40
0
0
0
0
40
20
10
% S
% Thr:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
40
% T
% Val:
0
10
0
0
10
10
40
0
50
10
60
10
0
20
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _