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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GPN1 All Species: 19.39
Human Site: S228 Identified Species: 35.56
UniProt: Q9HCN4 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HCN4 NP_001138519.1 374 41740 S228 S N L T R S M S L V L D E F Y
Chimpanzee Pan troglodytes XP_525723 374 41805 S228 S N L T R S M S L V L D E F Y
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_850503 374 41748 S228 S N L T R S M S L V L D E F Y
Cat Felis silvestris
Mouse Mus musculus Q8VCE2 372 41579 S228 S N L T R S M S L V L D E F Y
Rat Rattus norvegicus Q6R518 284 32784 V140 R V C G V F L V D S Q F M V E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509020 358 39911 L213 N L T R S M S L V L D E F Y S
Chicken Gallus gallus
Frog Xenopus laevis Q4V7Z0 285 33039 D141 V C G V F L V D S Q F M V E S
Zebra Danio Brachydanio rerio Q6PUR6 311 35074 M167 L C T S L S T M L H V E L P H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001121554 357 40182 Y213 I D I V E H S Y A V D W M Q D
Nematode Worm Caenorhab. elegans P46577 355 39639 L211 I V K P T F A L K W M Q D F E
Sea Urchin Strong. purpuratus XP_798140 332 36970 F188 R S V N P V T F M S N M L Y A
Poplar Tree Populus trichocarpa XP_002312316 407 45511 S262 G A M R S D D S Y M S T F S Q
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P47122 385 43176 S222 S S L V N S M S L M L E E F Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 N.A. 95.1 N.A. 90.6 22.9 N.A. 60.7 N.A. 21.9 22.9 N.A. N.A. 55.3 51.3 54
Protein Similarity: 100 99.4 N.A. 97.3 N.A. 93 39.2 N.A. 66.8 N.A. 40.1 42.2 N.A. N.A. 72.1 68.1 65.7
P-Site Identity: 100 100 N.A. 100 N.A. 100 0 N.A. 0 N.A. 0 13.3 N.A. N.A. 6.6 6.6 0
P-Site Similarity: 100 100 N.A. 100 N.A. 100 6.6 N.A. 33.3 N.A. 6.6 40 N.A. N.A. 20 20 26.6
Percent
Protein Identity: 49.3 N.A. N.A. N.A. 48.8 N.A.
Protein Similarity: 65.3 N.A. N.A. N.A. 64.4 N.A.
P-Site Identity: 6.6 N.A. N.A. N.A. 66.6 N.A.
P-Site Similarity: 20 N.A. N.A. N.A. 86.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 0 8 0 8 0 0 0 0 0 8 % A
% Cys: 0 16 8 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 8 8 8 8 0 16 31 8 0 8 % D
% Glu: 0 0 0 0 8 0 0 0 0 0 0 24 39 8 16 % E
% Phe: 0 0 0 0 8 16 0 8 0 0 8 8 16 47 0 % F
% Gly: 8 0 8 8 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 8 0 0 0 8 0 0 0 0 8 % H
% Ile: 16 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 8 0 0 0 0 0 8 0 0 0 0 0 0 % K
% Leu: 8 8 39 0 8 8 8 16 47 8 39 0 16 0 0 % L
% Met: 0 0 8 0 0 8 39 8 8 16 8 16 16 0 0 % M
% Asn: 8 31 0 8 8 0 0 0 0 0 8 0 0 0 0 % N
% Pro: 0 0 0 8 8 0 0 0 0 0 0 0 0 8 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 8 8 8 0 8 8 % Q
% Arg: 16 0 0 16 31 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 39 16 0 8 16 47 16 47 8 16 8 0 0 8 16 % S
% Thr: 0 0 16 31 8 0 16 0 0 0 0 8 0 0 0 % T
% Val: 8 16 8 24 8 8 8 8 8 39 8 0 8 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 8 0 8 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 8 8 0 0 0 0 16 39 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _