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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GPN1 All Species: 15.76
Human Site: T73 Identified Species: 28.89
UniProt: Q9HCN4 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HCN4 NP_001138519.1 374 41740 T73 A N I D I R D T V K Y K E V M
Chimpanzee Pan troglodytes XP_525723 374 41805 T73 A N I D I R D T V K Y K E V M
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_850503 374 41748 T73 A N I D I R D T V K Y K E V M
Cat Felis silvestris
Mouse Mus musculus Q8VCE2 372 41579 T73 A N I D I R D T V K Y K E V M
Rat Rattus norvegicus Q6R518 284 32784
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509020 358 39911 M64 T V K Y K E V M K Q Y G L G P
Chicken Gallus gallus
Frog Xenopus laevis Q4V7Z0 285 33039
Zebra Danio Brachydanio rerio Q6PUR6 311 35074 P18 F G Q V V I G P P G S G K T T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001121554 357 40182 K64 S V L Y K V K K P Y V I N L D
Nematode Worm Caenorhab. elegans P46577 355 39639 Y62 H A R K T P P Y V I N L D P A
Sea Urchin Strong. purpuratus XP_798140 332 36970 T39 G G L H N T D T K P P C L I V
Poplar Tree Populus trichocarpa XP_002312316 407 45511 N111 M T L P Y G A N I D I R D T V
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P47122 385 43176 Q68 K K V M E N Y Q L G P N G A I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 N.A. 95.1 N.A. 90.6 22.9 N.A. 60.7 N.A. 21.9 22.9 N.A. N.A. 55.3 51.3 54
Protein Similarity: 100 99.4 N.A. 97.3 N.A. 93 39.2 N.A. 66.8 N.A. 40.1 42.2 N.A. N.A. 72.1 68.1 65.7
P-Site Identity: 100 100 N.A. 100 N.A. 100 0 N.A. 6.6 N.A. 0 0 N.A. N.A. 0 6.6 13.3
P-Site Similarity: 100 100 N.A. 100 N.A. 100 0 N.A. 13.3 N.A. 0 13.3 N.A. N.A. 20 13.3 33.3
Percent
Protein Identity: 49.3 N.A. N.A. N.A. 48.8 N.A.
Protein Similarity: 65.3 N.A. N.A. N.A. 64.4 N.A.
P-Site Identity: 0 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 33.3 N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 31 8 0 0 0 0 8 0 0 0 0 0 0 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 0 0 0 31 0 0 39 0 0 8 0 0 16 0 8 % D
% Glu: 0 0 0 0 8 8 0 0 0 0 0 0 31 0 0 % E
% Phe: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 16 0 0 0 8 8 0 0 16 0 16 8 8 0 % G
% His: 8 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 31 0 31 8 0 0 8 8 8 8 0 8 8 % I
% Lys: 8 8 8 8 16 0 8 8 16 31 0 31 8 0 0 % K
% Leu: 0 0 24 0 0 0 0 0 8 0 0 8 16 8 0 % L
% Met: 8 0 0 8 0 0 0 8 0 0 0 0 0 0 31 % M
% Asn: 0 31 0 0 8 8 0 8 0 0 8 8 8 0 0 % N
% Pro: 0 0 0 8 0 8 8 8 16 8 16 0 0 8 8 % P
% Gln: 0 0 8 0 0 0 0 8 0 8 0 0 0 0 0 % Q
% Arg: 0 0 8 0 0 31 0 0 0 0 0 8 0 0 0 % R
% Ser: 8 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % S
% Thr: 8 8 0 0 8 8 0 39 0 0 0 0 0 16 8 % T
% Val: 0 16 8 8 8 8 8 0 39 0 8 0 0 31 16 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 16 8 0 8 8 0 8 39 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _