Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GPN1 All Species: 13.33
Human Site: Y118 Identified Species: 24.44
UniProt: Q9HCN4 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HCN4 NP_001138519.1 374 41740 Y118 K A Q N M S K Y V L I D T P G
Chimpanzee Pan troglodytes XP_525723 374 41805 Y118 K A Q N M S K Y V L I D T P G
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_850503 374 41748 Y118 K A Q N M S K Y V L I D T P G
Cat Felis silvestris
Mouse Mus musculus Q8VCE2 372 41579 Y118 K A Q N T F R Y V L I D T P G
Rat Rattus norvegicus Q6R518 284 32784 Q35 E A L N R S V Q V V N L D P A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509020 358 39911 P108 Q Y V L I D T P G Q I E V F T
Chicken Gallus gallus
Frog Xenopus laevis Q4V7Z0 285 33039 V36 T L N R S V Q V V N L D P A A
Zebra Danio Brachydanio rerio Q6PUR6 311 35074 A62 Y P C A V D I A E L V T L D D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001121554 357 40182 T108 G P N G G I V T A L N L F S T
Nematode Worm Caenorhab. elegans P46577 355 39639 L106 N G A I M T C L N L M C T R F
Sea Urchin Strong. purpuratus XP_798140 332 36970 E83 N L D P A V H E V G Y P T N I
Poplar Tree Populus trichocarpa XP_002312316 407 45511 R156 V I Q V I E K R A D Q L D Y V
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P47122 385 43176 C113 D T P G Q I E C F V W S A S G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 N.A. 95.1 N.A. 90.6 22.9 N.A. 60.7 N.A. 21.9 22.9 N.A. N.A. 55.3 51.3 54
Protein Similarity: 100 99.4 N.A. 97.3 N.A. 93 39.2 N.A. 66.8 N.A. 40.1 42.2 N.A. N.A. 72.1 68.1 65.7
P-Site Identity: 100 100 N.A. 100 N.A. 80 33.3 N.A. 6.6 N.A. 13.3 6.6 N.A. N.A. 6.6 20 13.3
P-Site Similarity: 100 100 N.A. 100 N.A. 86.6 46.6 N.A. 26.6 N.A. 26.6 20 N.A. N.A. 6.6 33.3 13.3
Percent
Protein Identity: 49.3 N.A. N.A. N.A. 48.8 N.A.
Protein Similarity: 65.3 N.A. N.A. N.A. 64.4 N.A.
P-Site Identity: 13.3 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 20 N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 39 8 8 8 0 0 8 16 0 0 0 8 8 16 % A
% Cys: 0 0 8 0 0 0 8 8 0 0 0 8 0 0 0 % C
% Asp: 8 0 8 0 0 16 0 0 0 8 0 39 16 8 8 % D
% Glu: 8 0 0 0 0 8 8 8 8 0 0 8 0 0 0 % E
% Phe: 0 0 0 0 0 8 0 0 8 0 0 0 8 8 8 % F
% Gly: 8 8 0 16 8 0 0 0 8 8 0 0 0 0 39 % G
% His: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 8 16 16 8 0 0 0 39 0 0 0 8 % I
% Lys: 31 0 0 0 0 0 31 0 0 0 0 0 0 0 0 % K
% Leu: 0 16 8 8 0 0 0 8 0 54 8 24 8 0 0 % L
% Met: 0 0 0 0 31 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 16 0 16 39 0 0 0 0 8 8 16 0 0 8 0 % N
% Pro: 0 16 8 8 0 0 0 8 0 0 0 8 8 39 0 % P
% Gln: 8 0 39 0 8 0 8 8 0 8 8 0 0 0 0 % Q
% Arg: 0 0 0 8 8 0 8 8 0 0 0 0 0 8 0 % R
% Ser: 0 0 0 0 8 31 0 0 0 0 0 8 0 16 0 % S
% Thr: 8 8 0 0 8 8 8 8 0 0 0 8 47 0 16 % T
% Val: 8 0 8 8 8 16 16 8 54 16 8 0 8 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % W
% Tyr: 8 8 0 0 0 0 0 31 0 0 8 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _