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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GPN1 All Species: 18.18
Human Site: Y219 Identified Species: 33.33
UniProt: Q9HCN4 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HCN4 NP_001138519.1 374 41740 Y219 A L N Q E T T Y V S N L T R S
Chimpanzee Pan troglodytes XP_525723 374 41805 Y219 A L N Q E T T Y V S N L T R S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_850503 374 41748 Y219 A L N Q E T T Y V S N L T R S
Cat Felis silvestris
Mouse Mus musculus Q8VCE2 372 41579 Y219 A L N Q E T T Y V S N L T R S
Rat Rattus norvegicus Q6R518 284 32784 E131 V Q Q L E Q W E F R V C G V F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509020 358 39911 A204 L N Q E T T Y A S N L T R S M
Chicken Gallus gallus
Frog Xenopus laevis Q4V7Z0 285 33039 F132 E Q L Q Q W E F R V C G V F L
Zebra Danio Brachydanio rerio Q6PUR6 311 35074 S158 A D P A K F I S V L C T S L S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001121554 357 40182 N204 L P F I V A M N K I D I V E H
Nematode Worm Caenorhab. elegans P46577 355 39639 A202 F I V V F N K A D I V K P T F
Sea Urchin Strong. purpuratus XP_798140 332 36970 T179 V V V Y V M D T A R S V N P V
Poplar Tree Populus trichocarpa XP_002312316 407 45511 F253 W M E D F E A F Q G A M R S D
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P47122 385 43176 Y213 D N G L G S G Y M S S L V N S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 N.A. 95.1 N.A. 90.6 22.9 N.A. 60.7 N.A. 21.9 22.9 N.A. N.A. 55.3 51.3 54
Protein Similarity: 100 99.4 N.A. 97.3 N.A. 93 39.2 N.A. 66.8 N.A. 40.1 42.2 N.A. N.A. 72.1 68.1 65.7
P-Site Identity: 100 100 N.A. 100 N.A. 100 6.6 N.A. 6.6 N.A. 6.6 20 N.A. N.A. 0 0 0
P-Site Similarity: 100 100 N.A. 100 N.A. 100 6.6 N.A. 20 N.A. 20 33.3 N.A. N.A. 13.3 6.6 20
Percent
Protein Identity: 49.3 N.A. N.A. N.A. 48.8 N.A.
Protein Similarity: 65.3 N.A. N.A. N.A. 64.4 N.A.
P-Site Identity: 0 N.A. N.A. N.A. 26.6 N.A.
P-Site Similarity: 20 N.A. N.A. N.A. 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 39 0 0 8 0 8 8 16 8 0 8 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 16 8 0 0 0 % C
% Asp: 8 8 0 8 0 0 8 0 8 0 8 0 0 0 8 % D
% Glu: 8 0 8 8 39 8 8 8 0 0 0 0 0 8 0 % E
% Phe: 8 0 8 0 16 8 0 16 8 0 0 0 0 8 16 % F
% Gly: 0 0 8 0 8 0 8 0 0 8 0 8 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % H
% Ile: 0 8 0 8 0 0 8 0 0 16 0 8 0 0 0 % I
% Lys: 0 0 0 0 8 0 8 0 8 0 0 8 0 0 0 % K
% Leu: 16 31 8 16 0 0 0 0 0 8 8 39 0 8 8 % L
% Met: 0 8 0 0 0 8 8 0 8 0 0 8 0 0 8 % M
% Asn: 0 16 31 0 0 8 0 8 0 8 31 0 8 8 0 % N
% Pro: 0 8 8 0 0 0 0 0 0 0 0 0 8 8 0 % P
% Gln: 0 16 16 39 8 8 0 0 8 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 8 16 0 0 16 31 0 % R
% Ser: 0 0 0 0 0 8 0 8 8 39 16 0 8 16 47 % S
% Thr: 0 0 0 0 8 39 31 8 0 0 0 16 31 8 0 % T
% Val: 16 8 16 8 16 0 0 0 39 8 16 8 24 8 8 % V
% Trp: 8 0 0 0 0 8 8 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 8 39 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _