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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPN1
All Species:
14.24
Human Site:
Y273
Identified Species:
26.11
UniProt:
Q9HCN4
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCN4
NP_001138519.1
374
41740
Y273
E
R
E
Y
R
P
E
Y
E
R
L
K
K
S
L
Chimpanzee
Pan troglodytes
XP_525723
374
41805
Y273
E
R
E
Y
R
P
E
Y
E
R
L
K
K
S
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_850503
374
41748
Y273
E
R
E
Y
R
P
E
Y
E
R
L
K
K
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCE2
372
41579
Y273
E
R
E
Y
R
P
E
Y
E
R
L
K
K
S
L
Rat
Rattus norvegicus
Q6R518
284
32784
K185
L
L
S
K
K
A
K
K
E
I
E
K
F
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509020
358
39911
E258
R
E
Y
R
P
E
Y
E
R
L
K
K
S
L
S
Chicken
Gallus gallus
Frog
Xenopus laevis
Q4V7Z0
285
33039
E186
L
S
K
K
A
K
K
E
I
E
K
F
L
D
P
Zebra Danio
Brachydanio rerio
Q6PUR6
311
35074
A212
Y
L
V
E
H
L
S
A
D
P
F
F
R
N
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121554
357
40182
V258
S
H
L
R
S
C
G
V
S
A
A
T
G
A
G
Nematode Worm
Caenorhab. elegans
P46577
355
39639
S256
G
L
K
T
V
C
V
S
S
A
T
G
E
G
F
Sea Urchin
Strong. purpuratus
XP_798140
332
36970
D233
T
D
F
E
T
F
Q
D
A
L
N
Q
E
T
S
Poplar Tree
Populus trichocarpa
XP_002312316
407
45511
E307
K
A
I
E
A
S
A
E
E
Y
M
E
T
Y
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P47122
385
43176
R267
D
Q
Y
Y
K
Q
E
R
E
K
A
L
N
L
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
N.A.
95.1
N.A.
90.6
22.9
N.A.
60.7
N.A.
21.9
22.9
N.A.
N.A.
55.3
51.3
54
Protein Similarity:
100
99.4
N.A.
97.3
N.A.
93
39.2
N.A.
66.8
N.A.
40.1
42.2
N.A.
N.A.
72.1
68.1
65.7
P-Site Identity:
100
100
N.A.
100
N.A.
100
13.3
N.A.
6.6
N.A.
0
0
N.A.
N.A.
0
0
0
P-Site Similarity:
100
100
N.A.
100
N.A.
100
26.6
N.A.
6.6
N.A.
13.3
20
N.A.
N.A.
6.6
13.3
26.6
Percent
Protein Identity:
49.3
N.A.
N.A.
N.A.
48.8
N.A.
Protein Similarity:
65.3
N.A.
N.A.
N.A.
64.4
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
16
8
8
8
8
16
16
0
0
8
0
% A
% Cys:
0
0
0
0
0
16
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
0
0
0
0
8
8
0
0
0
0
8
8
% D
% Glu:
31
8
31
24
0
8
39
24
54
8
8
8
16
0
0
% E
% Phe:
0
0
8
0
0
8
0
0
0
0
8
16
8
0
16
% F
% Gly:
8
0
0
0
0
0
8
0
0
0
0
8
8
8
8
% G
% His:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
8
8
0
0
0
0
0
% I
% Lys:
8
0
16
16
16
8
16
8
0
8
16
47
31
0
16
% K
% Leu:
16
24
8
0
0
8
0
0
0
16
31
8
8
24
31
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
0
8
8
0
% N
% Pro:
0
0
0
0
8
31
0
0
0
8
0
0
0
0
8
% P
% Gln:
0
8
0
0
0
8
8
0
0
0
0
8
0
0
0
% Q
% Arg:
8
31
0
16
31
0
0
8
8
31
0
0
8
0
0
% R
% Ser:
8
8
8
0
8
8
8
8
16
0
0
0
8
31
16
% S
% Thr:
8
0
0
8
8
0
0
0
0
0
8
8
8
8
0
% T
% Val:
0
0
8
0
8
0
8
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
16
39
0
0
8
31
0
8
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _