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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HHATL All Species: 9.09
Human Site: S46 Identified Species: 25
UniProt: Q9HCP6 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HCP6 NP_065758.3 504 56703 S46 H R K A F R E S V R P G W E Y
Chimpanzee Pan troglodytes XP_001169263 625 70145 A109 C S E D A R C A A P P K G S S
Rhesus Macaque Macaca mulatta XP_001108726 437 48773 G13 A L P T A E L G L Y S L V L S
Dog Lupus familis XP_534234 504 56898 S46 H R K A F R E S V R P G W E Y
Cat Felis silvestris
Mouse Mus musculus Q9D1G3 503 56412 S46 H R K A F R E S V R P G W E Y
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_418497 498 57269 W46 R D G I K P G W H Y F G R K M
Frog Xenopus laevis NP_001079492 503 58542 N46 D R K S F R E N I K E G W H Y
Zebra Danio Brachydanio rerio NP_957181 511 58768 N46 N R R A F R E N V K P G W H Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VZU2 500 58087 P49 K E A K F Q F P E G W S L Y P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 25.9 83.3 94 N.A. 90.8 N.A. N.A. N.A. 67.4 65.4 63.5 N.A. 23 N.A. N.A. N.A.
Protein Similarity: 100 39.8 84.5 97.2 N.A. 96 N.A. N.A. N.A. 81.3 79.7 78.8 N.A. 40.4 N.A. N.A. N.A.
P-Site Identity: 100 13.3 0 100 N.A. 100 N.A. N.A. N.A. 6.6 53.3 66.6 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 26.6 6.6 100 N.A. 100 N.A. N.A. N.A. 13.3 80 93.3 N.A. 13.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 12 45 23 0 0 12 12 0 0 0 0 0 0 % A
% Cys: 12 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % C
% Asp: 12 12 0 12 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 12 12 0 0 12 56 0 12 0 12 0 0 34 0 % E
% Phe: 0 0 0 0 67 0 12 0 0 0 12 0 0 0 0 % F
% Gly: 0 0 12 0 0 0 12 12 0 12 0 67 12 0 0 % G
% His: 34 0 0 0 0 0 0 0 12 0 0 0 0 23 0 % H
% Ile: 0 0 0 12 0 0 0 0 12 0 0 0 0 0 0 % I
% Lys: 12 0 45 12 12 0 0 0 0 23 0 12 0 12 0 % K
% Leu: 0 12 0 0 0 0 12 0 12 0 0 12 12 12 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % M
% Asn: 12 0 0 0 0 0 0 23 0 0 0 0 0 0 0 % N
% Pro: 0 0 12 0 0 12 0 12 0 12 56 0 0 0 12 % P
% Gln: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % Q
% Arg: 12 56 12 0 0 67 0 0 0 34 0 0 12 0 0 % R
% Ser: 0 12 0 12 0 0 0 34 0 0 12 12 0 12 23 % S
% Thr: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 45 0 0 0 12 0 0 % V
% Trp: 0 0 0 0 0 0 0 12 0 0 12 0 56 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 23 0 0 0 12 56 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _