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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HHATL
All Species:
9.09
Human Site:
T453
Identified Species:
25
UniProt:
Q9HCP6
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCP6
NP_065758.3
504
56703
T453
S
L
N
S
L
K
F
T
E
L
V
A
R
R
L
Chimpanzee
Pan troglodytes
XP_001169263
625
70145
L579
I
L
S
N
L
V
F
L
G
G
N
E
V
G
K
Rhesus Macaque
Macaca mulatta
XP_001108726
437
48773
C394
Y
L
W
S
F
L
N
C
F
G
L
N
F
E
L
Dog
Lupus familis
XP_534234
504
56898
T453
S
L
N
S
L
E
F
T
E
L
V
A
R
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9D1G3
503
56412
T452
S
L
N
S
L
E
F
T
E
L
V
A
R
R
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418497
498
57269
A448
A
L
N
S
L
E
F
A
L
L
V
T
R
R
L
Frog
Xenopus laevis
NP_001079492
503
58542
A453
A
L
N
S
L
D
F
A
L
L
V
A
K
R
L
Zebra Danio
Brachydanio rerio
NP_957181
511
58768
A454
A
L
N
S
L
D
F
A
Q
L
V
A
K
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VZU2
500
58087
I454
Y
F
I
G
G
Q
E
I
G
D
F
L
M
R
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
25.9
83.3
94
N.A.
90.8
N.A.
N.A.
N.A.
67.4
65.4
63.5
N.A.
23
N.A.
N.A.
N.A.
Protein Similarity:
100
39.8
84.5
97.2
N.A.
96
N.A.
N.A.
N.A.
81.3
79.7
78.8
N.A.
40.4
N.A.
N.A.
N.A.
P-Site Identity:
100
20
20
93.3
N.A.
93.3
N.A.
N.A.
N.A.
66.6
66.6
66.6
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
26.6
100
N.A.
100
N.A.
N.A.
N.A.
80
80
86.6
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
0
0
0
0
0
0
34
0
0
0
56
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
23
0
0
0
12
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
34
12
0
34
0
0
12
0
12
0
% E
% Phe:
0
12
0
0
12
0
78
0
12
0
12
0
12
0
0
% F
% Gly:
0
0
0
12
12
0
0
0
23
23
0
0
0
12
12
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
12
0
12
0
0
0
0
12
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
12
0
0
0
0
0
0
23
0
12
% K
% Leu:
0
89
0
0
78
12
0
12
23
67
12
12
0
0
78
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% M
% Asn:
0
0
67
12
0
0
12
0
0
0
12
12
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
12
0
0
12
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
45
78
0
% R
% Ser:
34
0
12
78
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
34
0
0
0
12
0
0
0
% T
% Val:
0
0
0
0
0
12
0
0
0
0
67
0
12
0
0
% V
% Trp:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
23
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _