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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDE11A
All Species:
20.3
Human Site:
S117
Identified Species:
37.22
UniProt:
Q9HCR9
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCR9
NP_001070664.1
934
104811
S117
G
N
L
Q
R
R
A
S
Q
K
E
L
R
K
S
Chimpanzee
Pan troglodytes
XP_001154733
931
104409
S117
G
N
L
Q
R
R
A
S
Q
K
E
L
R
K
S
Rhesus Macaque
Macaca mulatta
XP_001097592
933
104746
S117
G
N
L
Q
R
R
A
S
Q
K
E
L
R
K
S
Dog
Lupus familis
XP_545544
1009
112832
R115
R
A
S
Q
K
E
L
R
K
S
F
A
R
S
K
Cat
Felis silvestris
Mouse
Mus musculus
P0C1Q2
933
104545
S117
G
S
L
Q
R
R
A
S
Q
K
E
L
R
K
S
Rat
Rattus norvegicus
Q8VID6
935
104553
S117
G
N
L
Q
R
R
A
S
Q
K
E
L
R
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515351
961
106911
C125
P
T
A
L
D
Y
K
C
H
L
R
R
H
S
Q
Chicken
Gallus gallus
P52731
862
99990
P108
C
R
S
R
N
G
I
P
E
V
A
T
R
L
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689838
865
97719
L111
S
M
R
R
R
A
L
L
R
K
A
S
S
L
P
Tiger Blowfish
Takifugu rubipres
Q1KKS3
903
102001
A114
L
T
S
M
R
R
R
A
L
L
R
K
A
S
S
Fruit Fly
Dros. melanogaster
Q9VJ79
1451
160911
Q163
S
A
T
P
Q
Q
Q
Q
Q
Y
Q
V
Q
Q
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P91119
710
81117
Sea Urchin
Strong. purpuratus
XP_001185423
1005
112913
S176
P
V
R
P
R
S
G
S
R
Q
Y
L
R
Q
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
98.3
86.3
N.A.
94.5
93.9
N.A.
77.4
24.1
N.A.
77.8
80.7
30.5
N.A.
27.5
45.7
Protein Similarity:
100
99
99.3
88.5
N.A.
96.4
96.2
N.A.
82.7
45.1
N.A.
83.7
86.8
42.5
N.A.
45.6
61.1
P-Site Identity:
100
100
100
13.3
N.A.
93.3
100
N.A.
0
6.6
N.A.
13.3
20
6.6
N.A.
0
26.6
P-Site Similarity:
100
100
100
26.6
N.A.
100
100
N.A.
0
20
N.A.
26.6
26.6
46.6
N.A.
0
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
8
0
0
8
39
8
0
0
16
8
8
0
0
% A
% Cys:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% D
% Glu:
0
0
0
0
0
8
0
0
8
0
39
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
39
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
8
0
8
0
8
47
0
8
0
39
8
% K
% Leu:
8
0
39
8
0
0
16
8
8
16
0
47
0
16
8
% L
% Met:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
31
0
0
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
16
0
0
16
0
0
0
8
0
0
0
0
0
0
16
% P
% Gln:
0
0
0
47
8
8
8
8
47
8
8
0
8
16
8
% Q
% Arg:
8
8
16
16
62
47
8
8
16
0
16
8
62
0
0
% R
% Ser:
16
8
24
0
0
8
0
47
0
8
0
8
8
24
47
% S
% Thr:
0
16
8
0
0
0
0
0
0
0
0
8
0
0
0
% T
% Val:
0
8
0
0
0
0
0
0
0
8
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
8
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _