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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDE11A
All Species:
19.7
Human Site:
S163
Identified Species:
36.11
UniProt:
Q9HCR9
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCR9
NP_001070664.1
934
104811
S163
A
L
L
R
K
A
S
S
L
P
P
T
T
A
H
Chimpanzee
Pan troglodytes
XP_001154733
931
104409
S163
A
L
L
R
K
A
S
S
L
P
P
T
T
A
H
Rhesus Macaque
Macaca mulatta
XP_001097592
933
104746
S163
A
L
L
R
K
A
S
S
L
P
P
T
T
A
H
Dog
Lupus familis
XP_545544
1009
112832
T161
A
S
S
L
P
P
T
T
A
H
I
L
S
A
L
Cat
Felis silvestris
Mouse
Mus musculus
P0C1Q2
933
104545
S163
A
L
L
R
K
A
S
S
L
P
P
T
T
A
H
Rat
Rattus norvegicus
Q8VID6
935
104553
S163
A
L
L
R
K
A
S
S
L
P
P
T
T
A
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515351
961
106911
L171
V
D
A
H
R
G
S
L
F
L
V
E
A
T
A
Chicken
Gallus gallus
P52731
862
99990
N154
A
H
T
K
K
F
F
N
I
P
D
V
K
K
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689838
865
97719
F157
K
E
H
N
E
R
E
F
F
L
E
L
V
K
D
Tiger Blowfish
Takifugu rubipres
Q1KKS3
903
102001
R160
Y
L
K
E
H
N
E
R
E
F
F
L
E
L
V
Fruit Fly
Dros. melanogaster
Q9VJ79
1451
160911
F209
W
L
D
E
N
Q
E
F
V
Q
D
Y
F
I
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P91119
710
81117
Sea Urchin
Strong. purpuratus
XP_001185423
1005
112913
G222
S
P
K
E
R
A
M
G
D
G
T
G
K
G
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
98.3
86.3
N.A.
94.5
93.9
N.A.
77.4
24.1
N.A.
77.8
80.7
30.5
N.A.
27.5
45.7
Protein Similarity:
100
99
99.3
88.5
N.A.
96.4
96.2
N.A.
82.7
45.1
N.A.
83.7
86.8
42.5
N.A.
45.6
61.1
P-Site Identity:
100
100
100
13.3
N.A.
100
100
N.A.
6.6
20
N.A.
0
6.6
6.6
N.A.
0
6.6
P-Site Similarity:
100
100
100
33.3
N.A.
100
100
N.A.
13.3
46.6
N.A.
6.6
6.6
13.3
N.A.
0
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
54
0
8
0
0
47
0
0
8
0
0
0
8
47
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
0
0
0
0
0
8
0
16
0
0
0
8
% D
% Glu:
0
8
0
24
8
0
24
0
8
0
8
8
8
0
0
% E
% Phe:
0
0
0
0
0
8
8
16
16
8
8
0
8
0
8
% F
% Gly:
0
0
0
0
0
8
0
8
0
8
0
8
0
8
0
% G
% His:
0
8
8
8
8
0
0
0
0
8
0
0
0
0
39
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
8
0
0
8
0
% I
% Lys:
8
0
16
8
47
0
0
0
0
0
0
0
16
16
0
% K
% Leu:
0
54
39
8
0
0
0
8
39
16
0
24
0
8
8
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
8
8
0
8
0
0
0
0
0
0
8
% N
% Pro:
0
8
0
0
8
8
0
0
0
47
39
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% Q
% Arg:
0
0
0
39
16
8
0
8
0
0
0
0
0
0
8
% R
% Ser:
8
8
8
0
0
0
47
39
0
0
0
0
8
0
0
% S
% Thr:
0
0
8
0
0
0
8
8
0
0
8
39
39
8
0
% T
% Val:
8
0
0
0
0
0
0
0
8
0
8
8
8
0
8
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _