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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDE11A
All Species:
22.73
Human Site:
S441
Identified Species:
41.67
UniProt:
Q9HCR9
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCR9
NP_001070664.1
934
104811
S441
P
V
V
K
F
T
K
S
F
E
L
M
S
P
K
Chimpanzee
Pan troglodytes
XP_001154733
931
104409
S441
P
V
V
K
F
T
K
S
F
E
L
M
S
P
K
Rhesus Macaque
Macaca mulatta
XP_001097592
933
104746
S441
P
V
V
K
F
T
K
S
F
E
L
L
S
P
K
Dog
Lupus familis
XP_545544
1009
112832
S434
P
V
V
K
F
T
K
S
F
E
L
M
S
P
K
Cat
Felis silvestris
Mouse
Mus musculus
P0C1Q2
933
104545
S441
P
V
V
K
F
T
K
S
F
E
L
M
S
P
K
Rat
Rattus norvegicus
Q8VID6
935
104553
S441
P
V
V
K
F
T
K
S
F
E
L
M
S
P
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515351
961
106911
K468
V
L
N
R
L
D
G
K
P
F
D
N
A
D
Q
Chicken
Gallus gallus
P52731
862
99990
E419
K
P
F
D
E
Y
D
E
Q
I
I
E
T
L
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689838
865
97719
I422
D
W
L
I
N
N
S
I
A
E
L
V
A
S
T
Tiger Blowfish
Takifugu rubipres
Q1KKS3
903
102001
N426
S
Y
S
D
W
L
I
N
N
S
I
A
E
L
V
Fruit Fly
Dros. melanogaster
Q9VJ79
1451
160911
D643
G
S
F
S
R
V
F
D
F
E
A
N
D
L
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P91119
710
81117
I267
V
D
S
K
N
A
Q
I
Y
A
R
I
F
D
V
Sea Urchin
Strong. purpuratus
XP_001185423
1005
112913
V525
E
T
I
T
F
S
K
V
F
D
L
P
G
S
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
98.3
86.3
N.A.
94.5
93.9
N.A.
77.4
24.1
N.A.
77.8
80.7
30.5
N.A.
27.5
45.7
Protein Similarity:
100
99
99.3
88.5
N.A.
96.4
96.2
N.A.
82.7
45.1
N.A.
83.7
86.8
42.5
N.A.
45.6
61.1
P-Site Identity:
100
100
93.3
100
N.A.
100
100
N.A.
0
0
N.A.
13.3
0
13.3
N.A.
6.6
26.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
26.6
13.3
N.A.
33.3
20
13.3
N.A.
26.6
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
8
8
8
8
16
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
16
0
8
8
8
0
8
8
0
8
16
0
% D
% Glu:
8
0
0
0
8
0
0
8
0
62
0
8
8
0
0
% E
% Phe:
0
0
16
0
54
0
8
0
62
8
0
0
8
0
0
% F
% Gly:
8
0
0
0
0
0
8
0
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
8
0
0
8
16
0
8
16
8
0
0
0
% I
% Lys:
8
0
0
54
0
0
54
8
0
0
0
0
0
0
47
% K
% Leu:
0
8
8
0
8
8
0
0
0
0
62
8
0
24
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
39
0
0
0
% M
% Asn:
0
0
8
0
16
8
0
8
8
0
0
16
0
0
0
% N
% Pro:
47
8
0
0
0
0
0
0
8
0
0
8
0
47
0
% P
% Gln:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
8
% Q
% Arg:
0
0
0
8
8
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
8
8
16
8
0
8
8
47
0
8
0
0
47
16
8
% S
% Thr:
0
8
0
8
0
47
0
0
0
0
0
0
8
0
24
% T
% Val:
16
47
47
0
0
8
0
8
0
0
0
8
0
0
16
% V
% Trp:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
8
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _