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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDE11A All Species: 18.18
Human Site: S64 Identified Species: 33.33
UniProt: Q9HCR9 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HCR9 NP_001070664.1 934 104811 S64 G T S S L A H S T C R G G S S
Chimpanzee Pan troglodytes XP_001154733 931 104409 S64 G T S S L A H S T C R G G S S
Rhesus Macaque Macaca mulatta XP_001097592 933 104746 S64 G T S S L A H S T C K G G S S
Dog Lupus familis XP_545544 1009 112832 G62 V A G T G T G G G A H G G G T
Cat Felis silvestris
Mouse Mus musculus P0C1Q2 933 104545 S64 G A S S L A Q S N A K G S P G
Rat Rattus norvegicus Q8VID6 935 104553 S64 G A S S L A Q S S A R G S T G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515351 961 106911 A72 E E P A G V S A L A R P Q E R
Chicken Gallus gallus P52731 862 99990 R55 V S F K D M S R L E E C N I L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_689838 865 97719 W58 S A C A K D S W A S R G D G L
Tiger Blowfish Takifugu rubipres Q1KKS3 903 102001 D61 E K S S V C K D S W A S K C D
Fruit Fly Dros. melanogaster Q9VJ79 1451 160911 T110 E H S L L I A T R H A G V P L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P91119 710 81117
Sea Urchin Strong. purpuratus XP_001185423 1005 112913 S123 P T N T P S P S S P S P I N N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.3 98.3 86.3 N.A. 94.5 93.9 N.A. 77.4 24.1 N.A. 77.8 80.7 30.5 N.A. 27.5 45.7
Protein Similarity: 100 99 99.3 88.5 N.A. 96.4 96.2 N.A. 82.7 45.1 N.A. 83.7 86.8 42.5 N.A. 45.6 61.1
P-Site Identity: 100 100 93.3 13.3 N.A. 46.6 53.3 N.A. 6.6 0 N.A. 13.3 13.3 20 N.A. 0 13.3
P-Site Similarity: 100 100 100 26.6 N.A. 53.3 66.6 N.A. 20 6.6 N.A. 20 26.6 26.6 N.A. 0 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 31 0 16 0 39 8 8 8 31 16 0 0 0 0 % A
% Cys: 0 0 8 0 0 8 0 0 0 24 0 8 0 8 0 % C
% Asp: 0 0 0 0 8 8 0 8 0 0 0 0 8 0 8 % D
% Glu: 24 8 0 0 0 0 0 0 0 8 8 0 0 8 0 % E
% Phe: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 39 0 8 0 16 0 8 8 8 0 0 62 31 16 16 % G
% His: 0 8 0 0 0 0 24 0 0 8 8 0 0 0 0 % H
% Ile: 0 0 0 0 0 8 0 0 0 0 0 0 8 8 0 % I
% Lys: 0 8 0 8 8 0 8 0 0 0 16 0 8 0 0 % K
% Leu: 0 0 0 8 47 0 0 0 16 0 0 0 0 0 24 % L
% Met: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 0 0 0 8 0 0 0 8 8 8 % N
% Pro: 8 0 8 0 8 0 8 0 0 8 0 16 0 16 0 % P
% Gln: 0 0 0 0 0 0 16 0 0 0 0 0 8 0 0 % Q
% Arg: 0 0 0 0 0 0 0 8 8 0 39 0 0 0 8 % R
% Ser: 8 8 54 47 0 8 24 47 24 8 8 8 16 24 24 % S
% Thr: 0 31 0 16 0 8 0 8 24 0 0 0 0 8 8 % T
% Val: 16 0 0 0 8 8 0 0 0 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 8 0 8 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _