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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDE11A
All Species:
11.82
Human Site:
S70
Identified Species:
21.67
UniProt:
Q9HCR9
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCR9
NP_001070664.1
934
104811
S70
H
S
T
C
R
G
G
S
S
V
G
G
G
T
G
Chimpanzee
Pan troglodytes
XP_001154733
931
104409
S70
H
S
T
C
R
G
G
S
S
V
G
G
G
T
G
Rhesus Macaque
Macaca mulatta
XP_001097592
933
104746
S70
H
S
T
C
K
G
G
S
S
I
G
G
G
I
G
Dog
Lupus familis
XP_545544
1009
112832
G68
G
G
G
A
H
G
G
G
T
G
P
N
G
S
A
Cat
Felis silvestris
Mouse
Mus musculus
P0C1Q2
933
104545
P70
Q
S
N
A
K
G
S
P
G
I
G
G
G
A
G
Rat
Rattus norvegicus
Q8VID6
935
104553
T70
Q
S
S
A
R
G
S
T
G
I
G
G
G
A
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515351
961
106911
E78
S
A
L
A
R
P
Q
E
R
P
G
G
G
R
R
Chicken
Gallus gallus
P52731
862
99990
I61
S
R
L
E
E
C
N
I
L
F
E
L
L
T
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689838
865
97719
G64
S
W
A
S
R
G
D
G
L
Q
R
R
A
S
Q
Tiger Blowfish
Takifugu rubipres
Q1KKS3
903
102001
C67
K
D
S
W
A
S
K
C
D
G
L
Q
R
R
A
Fruit Fly
Dros. melanogaster
Q9VJ79
1451
160911
P116
A
T
R
H
A
G
V
P
L
P
L
A
Q
H
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P91119
710
81117
Sea Urchin
Strong. purpuratus
XP_001185423
1005
112913
N129
P
S
S
P
S
P
I
N
N
P
P
I
Q
P
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
98.3
86.3
N.A.
94.5
93.9
N.A.
77.4
24.1
N.A.
77.8
80.7
30.5
N.A.
27.5
45.7
Protein Similarity:
100
99
99.3
88.5
N.A.
96.4
96.2
N.A.
82.7
45.1
N.A.
83.7
86.8
42.5
N.A.
45.6
61.1
P-Site Identity:
100
100
80
20
N.A.
40
46.6
N.A.
26.6
6.6
N.A.
13.3
0
6.6
N.A.
0
6.6
P-Site Similarity:
100
100
93.3
33.3
N.A.
53.3
66.6
N.A.
33.3
6.6
N.A.
20
6.6
13.3
N.A.
0
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
31
16
0
0
0
0
0
0
8
8
16
16
% A
% Cys:
0
0
0
24
0
8
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
8
0
8
0
0
0
0
0
0
% D
% Glu:
0
0
0
8
8
0
0
8
0
0
8
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
8
8
8
0
0
62
31
16
16
16
47
47
54
0
39
% G
% His:
24
0
0
8
8
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
0
0
8
8
0
24
0
8
0
8
8
% I
% Lys:
8
0
0
0
16
0
8
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
16
0
0
0
0
0
24
0
16
8
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
8
8
8
0
0
8
0
0
0
% N
% Pro:
8
0
0
8
0
16
0
16
0
24
16
0
0
8
0
% P
% Gln:
16
0
0
0
0
0
8
0
0
8
0
8
16
0
16
% Q
% Arg:
0
8
8
0
39
0
0
0
8
0
8
8
8
16
8
% R
% Ser:
24
47
24
8
8
8
16
24
24
0
0
0
0
16
0
% S
% Thr:
0
8
24
0
0
0
0
8
8
0
0
0
0
24
0
% T
% Val:
0
0
0
0
0
0
8
0
0
16
0
0
0
0
0
% V
% Trp:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _