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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDE11A
All Species:
31.82
Human Site:
S836
Identified Species:
58.33
UniProt:
Q9HCR9
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCR9
NP_001070664.1
934
104811
S836
Q
V
A
E
L
V
T
S
E
F
F
E
Q
G
D
Chimpanzee
Pan troglodytes
XP_001154733
931
104409
F836
A
E
L
V
T
S
E
F
F
E
Q
G
D
R
E
Rhesus Macaque
Macaca mulatta
XP_001097592
933
104746
S836
Q
V
A
E
L
V
T
S
E
F
F
E
Q
G
D
Dog
Lupus familis
XP_545544
1009
112832
S829
Q
V
A
E
L
V
T
S
E
F
F
E
Q
G
D
Cat
Felis silvestris
Mouse
Mus musculus
P0C1Q2
933
104545
S836
Q
V
A
E
L
V
T
S
E
F
F
E
Q
G
D
Rat
Rattus norvegicus
Q8VID6
935
104553
S836
Q
V
A
E
L
V
T
S
E
F
F
E
Q
G
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515351
961
106911
L841
S
K
W
E
E
M
H
L
K
Q
L
L
T
Q
A
Chicken
Gallus gallus
P52731
862
99990
K774
N
K
G
D
E
L
P
K
L
Q
V
G
F
I
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689838
865
97719
I777
L
K
L
T
P
S
A
I
F
D
R
N
R
K
D
Tiger Blowfish
Takifugu rubipres
Q1KKS3
903
102001
S790
K
V
A
E
L
V
T
S
E
F
F
E
Q
G
D
Fruit Fly
Dros. melanogaster
Q9VJ79
1451
160911
S1031
R
V
A
D
L
V
S
S
E
F
F
E
Q
G
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P91119
710
81117
R622
D
I
N
R
Q
E
H
R
L
L
T
Q
A
V
M
Sea Urchin
Strong. purpuratus
XP_001185423
1005
112913
S913
K
I
A
E
L
V
T
S
E
F
F
D
Q
G
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
98.3
86.3
N.A.
94.5
93.9
N.A.
77.4
24.1
N.A.
77.8
80.7
30.5
N.A.
27.5
45.7
Protein Similarity:
100
99
99.3
88.5
N.A.
96.4
96.2
N.A.
82.7
45.1
N.A.
83.7
86.8
42.5
N.A.
45.6
61.1
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
6.6
6.6
N.A.
6.6
93.3
80
N.A.
0
80
P-Site Similarity:
100
6.6
100
100
N.A.
100
100
N.A.
20
20
N.A.
13.3
100
100
N.A.
13.3
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
62
0
0
0
8
0
0
0
0
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
16
0
0
0
0
0
8
0
8
8
0
77
% D
% Glu:
0
8
0
62
16
8
8
0
62
8
0
54
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
8
16
62
62
0
8
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
0
16
0
62
0
% G
% His:
0
0
0
0
0
0
16
0
0
0
0
0
0
0
0
% H
% Ile:
0
16
0
0
0
0
0
8
0
0
0
0
0
8
0
% I
% Lys:
16
24
0
0
0
0
0
8
8
0
0
0
0
8
0
% K
% Leu:
8
0
16
0
62
8
0
8
16
8
8
8
0
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% M
% Asn:
8
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% P
% Gln:
39
0
0
0
8
0
0
0
0
16
8
8
62
8
0
% Q
% Arg:
8
0
0
8
0
0
0
8
0
0
8
0
8
8
0
% R
% Ser:
8
0
0
0
0
16
8
62
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
8
8
0
54
0
0
0
8
0
8
0
0
% T
% Val:
0
54
0
8
0
62
0
0
0
0
8
0
0
8
0
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _