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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDE11A
All Species:
19.09
Human Site:
Y137
Identified Species:
35
UniProt:
Q9HCR9
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCR9
NP_001070664.1
934
104811
Y137
A
I
H
V
N
R
T
Y
D
E
Q
V
T
S
R
Chimpanzee
Pan troglodytes
XP_001154733
931
104409
Y137
A
I
H
V
N
R
T
Y
D
E
Q
V
T
S
R
Rhesus Macaque
Macaca mulatta
XP_001097592
933
104746
Y137
A
I
H
V
N
R
T
Y
D
E
Q
A
T
S
R
Dog
Lupus familis
XP_545544
1009
112832
T135
R
T
Y
D
E
Q
V
T
S
R
A
Q
E
P
L
Cat
Felis silvestris
Mouse
Mus musculus
P0C1Q2
933
104545
Y137
A
I
H
V
N
R
T
Y
D
E
Q
V
T
S
R
Rat
Rattus norvegicus
Q8VID6
935
104553
Y137
A
I
H
V
N
R
T
Y
D
E
Q
V
T
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515351
961
106911
N145
E
L
V
K
D
V
S
N
D
L
D
L
T
S
L
Chicken
Gallus gallus
P52731
862
99990
V128
S
K
F
E
D
N
L
V
N
P
D
K
E
T
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689838
865
97719
S131
I
L
S
A
L
L
E
S
R
V
N
I
P
Q
Y
Tiger Blowfish
Takifugu rubipres
Q1KKS3
903
102001
L134
A
H
I
L
S
A
L
L
E
S
R
V
N
I
P
Fruit Fly
Dros. melanogaster
Q9VJ79
1451
160911
A183
Q
H
H
Y
H
H
Q
A
N
S
P
Q
H
H
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P91119
710
81117
Sea Urchin
Strong. purpuratus
XP_001185423
1005
112913
W196
S
K
T
V
F
S
T
W
A
A
G
T
G
A
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
98.3
86.3
N.A.
94.5
93.9
N.A.
77.4
24.1
N.A.
77.8
80.7
30.5
N.A.
27.5
45.7
Protein Similarity:
100
99
99.3
88.5
N.A.
96.4
96.2
N.A.
82.7
45.1
N.A.
83.7
86.8
42.5
N.A.
45.6
61.1
P-Site Identity:
100
100
93.3
0
N.A.
100
100
N.A.
20
0
N.A.
0
13.3
13.3
N.A.
0
20
P-Site Similarity:
100
100
93.3
13.3
N.A.
100
100
N.A.
46.6
26.6
N.A.
13.3
40
26.6
N.A.
0
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
47
0
0
8
0
8
0
8
8
8
8
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
16
0
0
0
47
0
16
0
0
0
0
% D
% Glu:
8
0
0
8
8
0
8
0
8
39
0
0
16
0
0
% E
% Phe:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
0
% G
% His:
0
16
47
0
8
8
0
0
0
0
0
0
8
8
0
% H
% Ile:
8
39
8
0
0
0
0
0
0
0
0
8
0
8
0
% I
% Lys:
0
16
0
8
0
0
0
0
0
0
0
8
0
0
0
% K
% Leu:
0
16
0
8
8
8
16
8
0
8
0
8
0
0
16
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
39
8
0
8
16
0
8
0
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
8
0
8
8
8
% P
% Gln:
8
0
0
0
0
8
8
0
0
0
39
16
0
8
0
% Q
% Arg:
8
0
0
0
0
39
0
0
8
8
8
0
0
0
54
% R
% Ser:
16
0
8
0
8
8
8
8
8
16
0
0
0
47
0
% S
% Thr:
0
8
8
0
0
0
47
8
0
0
0
8
47
8
0
% T
% Val:
0
0
8
47
0
8
8
8
0
8
0
39
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
8
0
0
0
39
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _