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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDE11A
All Species:
23.33
Human Site:
Y289
Identified Species:
42.78
UniProt:
Q9HCR9
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCR9
NP_001070664.1
934
104811
Y289
W
G
K
G
I
I
G
Y
V
G
E
H
G
E
T
Chimpanzee
Pan troglodytes
XP_001154733
931
104409
Y289
W
G
K
G
I
I
G
Y
V
G
E
H
G
E
T
Rhesus Macaque
Macaca mulatta
XP_001097592
933
104746
Y289
W
G
K
G
I
I
G
Y
V
G
E
H
G
E
T
Dog
Lupus familis
XP_545544
1009
112832
Y282
W
G
K
G
I
I
G
Y
V
G
E
H
G
E
T
Cat
Felis silvestris
Mouse
Mus musculus
P0C1Q2
933
104545
Y289
W
G
K
G
I
I
G
Y
V
G
E
H
G
E
T
Rat
Rattus norvegicus
Q8VID6
935
104553
Y289
W
G
K
G
I
I
G
Y
V
G
E
H
G
E
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515351
961
106911
Y314
F
A
A
S
R
K
E
Y
D
R
S
R
A
L
L
Chicken
Gallus gallus
P52731
862
99990
N273
Y
T
I
R
M
Y
L
N
C
E
R
Y
S
V
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689838
865
97719
M276
K
T
K
S
L
L
C
M
P
I
H
N
S
D
G
Tiger Blowfish
Takifugu rubipres
Q1KKS3
903
102001
M280
K
T
K
S
L
L
C
M
P
I
Q
N
S
D
G
Fruit Fly
Dros. melanogaster
Q9VJ79
1451
160911
H492
W
G
T
G
I
A
G
H
V
A
E
S
G
E
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P91119
710
81117
V121
G
E
L
K
L
K
K
V
K
T
S
K
S
A
D
Sea Urchin
Strong. purpuratus
XP_001185423
1005
112913
K374
V
G
E
S
L
I
G
K
V
A
E
T
G
R
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
98.3
86.3
N.A.
94.5
93.9
N.A.
77.4
24.1
N.A.
77.8
80.7
30.5
N.A.
27.5
45.7
Protein Similarity:
100
99
99.3
88.5
N.A.
96.4
96.2
N.A.
82.7
45.1
N.A.
83.7
86.8
42.5
N.A.
45.6
61.1
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
6.6
0
N.A.
6.6
6.6
60
N.A.
0
40
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
20
N.A.
33.3
40
66.6
N.A.
6.6
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
8
0
0
0
16
0
0
8
8
8
% A
% Cys:
0
0
0
0
0
0
16
0
8
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
8
0
0
0
0
16
8
% D
% Glu:
0
8
8
0
0
0
8
0
0
8
62
0
0
54
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
62
0
54
0
0
62
0
0
47
0
0
62
0
24
% G
% His:
0
0
0
0
0
0
0
8
0
0
8
47
0
0
0
% H
% Ile:
0
0
8
0
54
54
0
0
0
16
0
0
0
0
0
% I
% Lys:
16
0
62
8
0
16
8
8
8
0
0
8
0
0
0
% K
% Leu:
0
0
8
0
31
16
8
0
0
0
0
0
0
8
8
% L
% Met:
0
0
0
0
8
0
0
16
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
16
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
16
0
0
0
0
0
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Q
% Arg:
0
0
0
8
8
0
0
0
0
8
8
8
0
8
0
% R
% Ser:
0
0
0
31
0
0
0
0
0
0
16
8
31
0
0
% S
% Thr:
0
24
8
0
0
0
0
0
0
8
0
8
0
0
47
% T
% Val:
8
0
0
0
0
0
0
8
62
0
0
0
0
8
0
% V
% Trp:
54
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
8
0
54
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _