KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDE11A
All Species:
22.73
Human Site:
Y466
Identified Species:
41.67
UniProt:
Q9HCR9
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCR9
NP_001070664.1
934
104811
Y466
E
S
M
E
K
S
S
Y
S
D
W
L
I
N
N
Chimpanzee
Pan troglodytes
XP_001154733
931
104409
Y466
E
S
M
E
K
S
S
Y
S
D
W
L
I
N
N
Rhesus Macaque
Macaca mulatta
XP_001097592
933
104746
Y466
E
S
M
E
K
S
S
Y
S
D
W
L
I
N
N
Dog
Lupus familis
XP_545544
1009
112832
Y459
E
S
M
E
K
S
S
Y
S
D
W
L
I
N
N
Cat
Felis silvestris
Mouse
Mus musculus
P0C1Q2
933
104545
Y466
E
S
V
E
K
S
S
Y
S
D
W
L
I
N
N
Rat
Rattus norvegicus
Q8VID6
935
104553
Y466
E
S
V
E
K
S
S
Y
S
D
W
L
I
N
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515351
961
106911
I493
G
L
G
I
N
N
T
I
M
Y
D
Q
V
K
K
Chicken
Gallus gallus
P52731
862
99990
K444
D
T
Y
D
K
M
N
K
L
E
N
R
K
D
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689838
865
97719
E447
Q
D
P
R
F
D
A
E
A
D
Q
F
S
G
F
Tiger Blowfish
Takifugu rubipres
Q1KKS3
903
102001
F451
D
A
Y
Q
D
P
R
F
D
A
E
A
D
Q
F
Fruit Fly
Dros. melanogaster
Q9VJ79
1451
160911
N668
Y
E
S
R
F
P
I
N
I
G
I
T
G
H
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P91119
710
81117
I292
N
S
E
G
Q
K
E
I
R
F
D
M
S
K
G
Sea Urchin
Strong. purpuratus
XP_001185423
1005
112913
N550
S
G
D
I
K
L
A
N
G
I
I
E
Q
V
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
98.3
86.3
N.A.
94.5
93.9
N.A.
77.4
24.1
N.A.
77.8
80.7
30.5
N.A.
27.5
45.7
Protein Similarity:
100
99
99.3
88.5
N.A.
96.4
96.2
N.A.
82.7
45.1
N.A.
83.7
86.8
42.5
N.A.
45.6
61.1
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
0
6.6
N.A.
6.6
0
0
N.A.
6.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
46.6
N.A.
26.6
26.6
6.6
N.A.
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
16
0
8
8
0
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
8
8
8
8
8
0
0
8
54
16
0
8
8
0
% D
% Glu:
47
8
8
47
0
0
8
8
0
8
8
8
0
0
0
% E
% Phe:
0
0
0
0
16
0
0
8
0
8
0
8
0
0
16
% F
% Gly:
8
8
8
8
0
0
0
0
8
8
0
0
8
8
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
16
0
0
8
16
8
8
16
0
47
0
8
% I
% Lys:
0
0
0
0
62
8
0
8
0
0
0
0
8
16
8
% K
% Leu:
0
8
0
0
0
8
0
0
8
0
0
47
0
0
0
% L
% Met:
0
0
31
0
0
8
0
0
8
0
0
8
0
0
0
% M
% Asn:
8
0
0
0
8
8
8
16
0
0
8
0
0
47
47
% N
% Pro:
0
0
8
0
0
16
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
8
8
0
0
0
0
0
8
8
8
8
0
% Q
% Arg:
0
0
0
16
0
0
8
0
8
0
0
8
0
0
0
% R
% Ser:
8
54
8
0
0
47
47
0
47
0
0
0
16
0
0
% S
% Thr:
0
8
0
0
0
0
8
0
0
0
0
8
0
0
0
% T
% Val:
0
0
16
0
0
0
0
0
0
0
0
0
8
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
47
0
0
0
0
% W
% Tyr:
8
0
16
0
0
0
0
47
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _