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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDE11A All Species: 28.48
Human Site: Y796 Identified Species: 52.22
UniProt: Q9HCR9 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HCR9 NP_001070664.1 934 104811 Y796 E L V S K G E Y D W N I K N H
Chimpanzee Pan troglodytes XP_001154733 931 104409 Y796 E L V S K G E Y D W N I K N H
Rhesus Macaque Macaca mulatta XP_001097592 933 104746 Y796 E L V S K G E Y D W N I K N H
Dog Lupus familis XP_545544 1009 112832 Y789 E L V S K G E Y D W N I K S H
Cat Felis silvestris
Mouse Mus musculus P0C1Q2 933 104545 Y796 E L V R K G D Y D W S I T S H
Rat Rattus norvegicus Q8VID6 935 104553 Y796 E L V S K G A Y D W S I T S H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515351 961 106911 L801 D E L P R L Q L E W I D S I C
Chicken Gallus gallus P52731 862 99990 Q734 I T K P W E V Q S K V A L M V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_689838 865 97719 D737 S M L M T A C D L G A V T K P
Tiger Blowfish Takifugu rubipres Q1KKS3 903 102001 Y750 E L V S I G E Y N W N V K T H
Fruit Fly Dros. melanogaster Q9VJ79 1451 160911 S991 E S V S Q P T S Y W V A E E P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P91119 710 81117 T582 S S E D Y K K T L S L I K H C
Sea Urchin Strong. purpuratus XP_001185423 1005 112913 H873 E M I R N Q T H N W N S P Q N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.3 98.3 86.3 N.A. 94.5 93.9 N.A. 77.4 24.1 N.A. 77.8 80.7 30.5 N.A. 27.5 45.7
Protein Similarity: 100 99 99.3 88.5 N.A. 96.4 96.2 N.A. 82.7 45.1 N.A. 83.7 86.8 42.5 N.A. 45.6 61.1
P-Site Identity: 100 100 100 93.3 N.A. 66.6 73.3 N.A. 6.6 0 N.A. 0 73.3 26.6 N.A. 13.3 20
P-Site Similarity: 100 100 100 100 N.A. 86.6 86.6 N.A. 40 0 N.A. 20 86.6 40 N.A. 26.6 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 8 8 0 0 0 8 16 0 0 0 % A
% Cys: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 16 % C
% Asp: 8 0 0 8 0 0 8 8 47 0 0 8 0 0 0 % D
% Glu: 70 8 8 0 0 8 39 0 8 0 0 0 8 8 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 54 0 0 0 8 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 8 0 0 0 0 0 8 54 % H
% Ile: 8 0 8 0 8 0 0 0 0 0 8 54 0 8 0 % I
% Lys: 0 0 8 0 47 8 8 0 0 8 0 0 47 8 0 % K
% Leu: 0 54 16 0 0 8 0 8 16 0 8 0 8 0 0 % L
% Met: 0 16 0 8 0 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 0 0 0 0 8 0 0 0 16 0 47 0 0 24 8 % N
% Pro: 0 0 0 16 0 8 0 0 0 0 0 0 8 0 16 % P
% Gln: 0 0 0 0 8 8 8 8 0 0 0 0 0 8 0 % Q
% Arg: 0 0 0 16 8 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 16 16 0 54 0 0 0 8 8 8 16 8 8 24 0 % S
% Thr: 0 8 0 0 8 0 16 8 0 0 0 0 24 8 0 % T
% Val: 0 0 62 0 0 0 8 0 0 0 16 16 0 0 8 % V
% Trp: 0 0 0 0 8 0 0 0 0 77 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 54 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _