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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP4F12
All Species:
4.55
Human Site:
T165
Identified Species:
16.67
UniProt:
Q9HCS2
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCS2
NP_076433.2
524
60310
T165
N
I
L
K
S
Y
I
T
I
F
N
K
S
A
N
Chimpanzee
Pan troglodytes
XP_524141
524
60335
T165
N
I
L
K
S
Y
I
T
I
F
N
K
S
A
N
Rhesus Macaque
Macaca mulatta
XP_001112408
524
60103
K165
N
I
L
K
P
Y
I
K
I
F
N
K
S
A
T
Dog
Lupus familis
XP_541983
540
62222
K185
E
I
L
K
S
Y
V
K
I
F
N
R
S
A
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9EP75
524
59782
K165
N
I
L
K
P
Y
V
K
I
F
N
D
S
T
N
Rat
Rattus norvegicus
P33274
524
59850
K165
N
I
L
K
P
Y
V
K
I
F
N
D
S
T
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27589
501
57896
E143
K
I
L
E
Q
F
V
E
I
F
D
Q
Q
S
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.9
91.9
69.2
N.A.
75
75.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
33.9
N.A.
N.A.
N.A.
Protein Similarity:
100
98.4
95.4
79.6
N.A.
83.2
83.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
55.9
N.A.
N.A.
N.A.
P-Site Identity:
100
100
80
66.6
N.A.
66.6
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
80
86.6
N.A.
73.3
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
58
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
15
29
0
0
15
% D
% Glu:
15
0
0
15
0
0
0
15
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
15
0
0
0
100
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
100
0
0
0
0
43
0
100
0
0
0
0
0
0
% I
% Lys:
15
0
0
86
0
0
0
58
0
0
0
43
0
0
0
% K
% Leu:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
72
0
0
0
0
0
0
0
0
0
86
0
0
0
58
% N
% Pro:
0
0
0
0
43
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
15
0
0
0
0
0
0
15
15
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% R
% Ser:
0
0
0
0
43
0
0
0
0
0
0
0
86
15
0
% S
% Thr:
0
0
0
0
0
0
0
29
0
0
0
0
0
29
15
% T
% Val:
0
0
0
0
0
0
58
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
86
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _